M1-like tumor-associated macrophages cascade a mesenchymal/stem-like phenotype of oral squamous cell carcinoma via the IL6/Stat3/THBS1 feedback loop

BACKGROUND: Tumor-associated macrophages (TAMs) have a leading position in the tumor microenvironment. Previously, we have demonstrated that M1-like TAMs activated by exosome-transferred THBS1 promote malignant migration in oral squamous cell carcinoma (OSCC). However, the functional roles and assoc...

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Detalles Bibliográficos
Autores principales: You, Yuanhe, Tian, Zhuowei, Du, Zhong, Wu, Kailiu, Xu, Guisong, Dai, Meilu, Wang, Yan’an, Xiao, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734049/
https://www.ncbi.nlm.nih.gov/pubmed/34991668
http://dx.doi.org/10.1186/s13046-021-02222-z

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