Neddylation-dependent protein degradation is a nexus between synaptic insulin resistance, neuroinflammation and Alzheimer’s disease

BACKGROUND: The metabolic syndrome is a consequence of modern lifestyle that causes synaptic insulin resistance and cognitive deficits and that in interaction with a high amyloid load is an important risk factor for Alzheimer's disease. It has been proposed that neuroinflammation might be an in...

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Detalles Bibliográficos
Autores principales: Confettura, Alessandro Dario, Cuboni, Eleonora, Ammar, Mohamed Rafeet, Jia, Shaobo, Gomes, Guilherme M., Yuanxiang, PingAn, Raman, Rajeev, Li, Tingting, Grochowska, Katarzyna M., Ahrends, Robert, Karpova, Anna, Dityatev, Alexander, Kreutz, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734066/
https://www.ncbi.nlm.nih.gov/pubmed/34986876
http://dx.doi.org/10.1186/s40035-021-00277-8

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