Fatal case of disseminated cryptococcal infection and meningoencephalitis in the setting of prolonged glucocorticoid use in a Covid-19 positive patient

Based on the RECOVERY trial, glucocorticoids have become the mainstay of treatment for COVID-19, thus increasing the risk of opportunistic infections. We report a case of disseminated Cryptococcus neoformans with documented meningoencephalitis in a patient with severe COVID-19 in the setting of prol...

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Detalles Bibliográficos
Autores principales: Karnik, Krupa, Wu, Yuexiu, Ruddy, Samantha, Quijano-Rondan, Bladimir, Urban, Carl, Turett, Glenn, Yung, Lok, Prasad, Nishant, Yoon, James, Segal-Maurer, Sorana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734083/
https://www.ncbi.nlm.nih.gov/pubmed/35013707
http://dx.doi.org/10.1016/j.idcr.2022.e01380
Descripción
Sumario:Based on the RECOVERY trial, glucocorticoids have become the mainstay of treatment for COVID-19, thus increasing the risk of opportunistic infections. We report a case of disseminated Cryptococcus neoformans with documented meningoencephalitis in a patient with severe COVID-19 in the setting of prolonged glucocorticoid administration with poor outcome likely due to adrenal involvement.

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