Fatal case of disseminated cryptococcal infection and meningoencephalitis in the setting of prolonged glucocorticoid use in a Covid-19 positive patient

Based on the RECOVERY trial, glucocorticoids have become the mainstay of treatment for COVID-19, thus increasing the risk of opportunistic infections. We report a case of disseminated Cryptococcus neoformans with documented meningoencephalitis in a patient with severe COVID-19 in the setting of prol...

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Autores principales: Karnik, Krupa, Wu, Yuexiu, Ruddy, Samantha, Quijano-Rondan, Bladimir, Urban, Carl, Turett, Glenn, Yung, Lok, Prasad, Nishant, Yoon, James, Segal-Maurer, Sorana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734083/
https://www.ncbi.nlm.nih.gov/pubmed/35013707
http://dx.doi.org/10.1016/j.idcr.2022.e01380
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author Karnik, Krupa
Wu, Yuexiu
Ruddy, Samantha
Quijano-Rondan, Bladimir
Urban, Carl
Turett, Glenn
Yung, Lok
Prasad, Nishant
Yoon, James
Segal-Maurer, Sorana
author_facet Karnik, Krupa
Wu, Yuexiu
Ruddy, Samantha
Quijano-Rondan, Bladimir
Urban, Carl
Turett, Glenn
Yung, Lok
Prasad, Nishant
Yoon, James
Segal-Maurer, Sorana
author_sort Karnik, Krupa
collection PubMed
description Based on the RECOVERY trial, glucocorticoids have become the mainstay of treatment for COVID-19, thus increasing the risk of opportunistic infections. We report a case of disseminated Cryptococcus neoformans with documented meningoencephalitis in a patient with severe COVID-19 in the setting of prolonged glucocorticoid administration with poor outcome likely due to adrenal involvement.
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spelling pubmed-87340832022-01-06 Fatal case of disseminated cryptococcal infection and meningoencephalitis in the setting of prolonged glucocorticoid use in a Covid-19 positive patient Karnik, Krupa Wu, Yuexiu Ruddy, Samantha Quijano-Rondan, Bladimir Urban, Carl Turett, Glenn Yung, Lok Prasad, Nishant Yoon, James Segal-Maurer, Sorana IDCases Case Report Based on the RECOVERY trial, glucocorticoids have become the mainstay of treatment for COVID-19, thus increasing the risk of opportunistic infections. We report a case of disseminated Cryptococcus neoformans with documented meningoencephalitis in a patient with severe COVID-19 in the setting of prolonged glucocorticoid administration with poor outcome likely due to adrenal involvement. Elsevier 2022-01-06 /pmc/articles/PMC8734083/ /pubmed/35013707 http://dx.doi.org/10.1016/j.idcr.2022.e01380 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Karnik, Krupa
Wu, Yuexiu
Ruddy, Samantha
Quijano-Rondan, Bladimir
Urban, Carl
Turett, Glenn
Yung, Lok
Prasad, Nishant
Yoon, James
Segal-Maurer, Sorana
Fatal case of disseminated cryptococcal infection and meningoencephalitis in the setting of prolonged glucocorticoid use in a Covid-19 positive patient
title Fatal case of disseminated cryptococcal infection and meningoencephalitis in the setting of prolonged glucocorticoid use in a Covid-19 positive patient
title_full Fatal case of disseminated cryptococcal infection and meningoencephalitis in the setting of prolonged glucocorticoid use in a Covid-19 positive patient
title_fullStr Fatal case of disseminated cryptococcal infection and meningoencephalitis in the setting of prolonged glucocorticoid use in a Covid-19 positive patient
title_full_unstemmed Fatal case of disseminated cryptococcal infection and meningoencephalitis in the setting of prolonged glucocorticoid use in a Covid-19 positive patient
title_short Fatal case of disseminated cryptococcal infection and meningoencephalitis in the setting of prolonged glucocorticoid use in a Covid-19 positive patient
title_sort fatal case of disseminated cryptococcal infection and meningoencephalitis in the setting of prolonged glucocorticoid use in a covid-19 positive patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734083/
https://www.ncbi.nlm.nih.gov/pubmed/35013707
http://dx.doi.org/10.1016/j.idcr.2022.e01380
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