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Purposeful use of multimodality imaging in the diagnosis of caseous mitral annular calcification: a case series report
BACKGROUND: Caseous mitral annular calcification (CMAC) is a rare liquefactive variant of mitral annular calcification (MAC) and superficially mimics a cardiac vegetation or abscess. CMAC is viewed as a benign condition of MAC, while MAC has clinical implications for patients’ lives. Correctly diagn...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734157/ https://www.ncbi.nlm.nih.gov/pubmed/34991503 http://dx.doi.org/10.1186/s12880-021-00725-x |
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author | Sveric, Krunoslav Michael Platzek, Ivan Golgor, Elena Hoffmann, Ralf-Thorsten Linke, Axel Jellinghaus, Stefanie |
author_facet | Sveric, Krunoslav Michael Platzek, Ivan Golgor, Elena Hoffmann, Ralf-Thorsten Linke, Axel Jellinghaus, Stefanie |
author_sort | Sveric, Krunoslav Michael |
collection | PubMed |
description | BACKGROUND: Caseous mitral annular calcification (CMAC) is a rare liquefactive variant of mitral annular calcification (MAC) and superficially mimics a cardiac vegetation or abscess. CMAC is viewed as a benign condition of MAC, while MAC has clinical implications for patients’ lives. Correctly diagnosing CMAC is essential in order to avoid unnecessary interventions, cardiac surgery or even psychological suffering for the patient. CASE PRESENTATION: We report on 6 patients with suspected intra-cardiac masses of the mitral annulus that were referred to our institution for further clarification. A definitive diagnosis of CMAC was achieved by combining echocardiography (Echo), cardiac magnetic resonance imaging (MRI) and cardiac computed tomography (CT) for these patients. Echo assessed the mass itself and possible interactions with the mitral valve. MRI was useful in differentiating the tissue from other benign or malign neoplasms. CT revealed the typical structure of CMAC with a “soft” liquefied centre and an outer capsule with calcification. CONCLUSION: CMAC is a rare condition, and most clinicians and even radiologists are not familiar with it. CMAC can be mistaken for an intra-cardiac tumour, thombus, vegetation, or abscess. Non-invasive multimodality imaging (i.e. Echo, MRI, and CT) helps to establish a definitive diagnosis of CMAC and avoid unnecessary interventions especially in uncertain cases. |
format | Online Article Text |
id | pubmed-8734157 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-87341572022-01-07 Purposeful use of multimodality imaging in the diagnosis of caseous mitral annular calcification: a case series report Sveric, Krunoslav Michael Platzek, Ivan Golgor, Elena Hoffmann, Ralf-Thorsten Linke, Axel Jellinghaus, Stefanie BMC Med Imaging Case Report BACKGROUND: Caseous mitral annular calcification (CMAC) is a rare liquefactive variant of mitral annular calcification (MAC) and superficially mimics a cardiac vegetation or abscess. CMAC is viewed as a benign condition of MAC, while MAC has clinical implications for patients’ lives. Correctly diagnosing CMAC is essential in order to avoid unnecessary interventions, cardiac surgery or even psychological suffering for the patient. CASE PRESENTATION: We report on 6 patients with suspected intra-cardiac masses of the mitral annulus that were referred to our institution for further clarification. A definitive diagnosis of CMAC was achieved by combining echocardiography (Echo), cardiac magnetic resonance imaging (MRI) and cardiac computed tomography (CT) for these patients. Echo assessed the mass itself and possible interactions with the mitral valve. MRI was useful in differentiating the tissue from other benign or malign neoplasms. CT revealed the typical structure of CMAC with a “soft” liquefied centre and an outer capsule with calcification. CONCLUSION: CMAC is a rare condition, and most clinicians and even radiologists are not familiar with it. CMAC can be mistaken for an intra-cardiac tumour, thombus, vegetation, or abscess. Non-invasive multimodality imaging (i.e. Echo, MRI, and CT) helps to establish a definitive diagnosis of CMAC and avoid unnecessary interventions especially in uncertain cases. BioMed Central 2022-01-06 /pmc/articles/PMC8734157/ /pubmed/34991503 http://dx.doi.org/10.1186/s12880-021-00725-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Sveric, Krunoslav Michael Platzek, Ivan Golgor, Elena Hoffmann, Ralf-Thorsten Linke, Axel Jellinghaus, Stefanie Purposeful use of multimodality imaging in the diagnosis of caseous mitral annular calcification: a case series report |
title | Purposeful use of multimodality imaging in the diagnosis of caseous mitral annular calcification: a case series report |
title_full | Purposeful use of multimodality imaging in the diagnosis of caseous mitral annular calcification: a case series report |
title_fullStr | Purposeful use of multimodality imaging in the diagnosis of caseous mitral annular calcification: a case series report |
title_full_unstemmed | Purposeful use of multimodality imaging in the diagnosis of caseous mitral annular calcification: a case series report |
title_short | Purposeful use of multimodality imaging in the diagnosis of caseous mitral annular calcification: a case series report |
title_sort | purposeful use of multimodality imaging in the diagnosis of caseous mitral annular calcification: a case series report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734157/ https://www.ncbi.nlm.nih.gov/pubmed/34991503 http://dx.doi.org/10.1186/s12880-021-00725-x |
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