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Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study

BACKGROUND: A prospective cohort study of the clinical presentations and management outcomes of laboratory-confirmed COVID-19 patients in the early months of the pandemic was performed at two hospitals in Dar es Salaam, Tanzania. METHODS: Between April 1 and May 31, 2020, laboratory-confirmed COVID-...

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Detalles Bibliográficos
Autores principales: Mnyambwa, Nicholaus P., Lubinza, Clara, Ngadaya, Esther, Senkoro, Mbazi, Kimaro, Godfather, Kagaruki, Gibson B., Binagi, Stanley, Malima, Amani, Kazyoba, Paul, Oriyo, Ndekya, Mghamba, Janneth M., Fredrick, Aman, Ramaiya, Kaushik, Zumla, Alimuddin, Jaffar, Shabbar, Mfinanga, Sayoki G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734168/
https://www.ncbi.nlm.nih.gov/pubmed/35721420
http://dx.doi.org/10.1016/j.ijregi.2021.12.010
Descripción
Sumario:BACKGROUND: A prospective cohort study of the clinical presentations and management outcomes of laboratory-confirmed COVID-19 patients in the early months of the pandemic was performed at two hospitals in Dar es Salaam, Tanzania. METHODS: Between April 1 and May 31, 2020, laboratory-confirmed COVID-19 patients seen at two tertiary facilities were consecutively enrolled in the study and followed up for 21 days. RESULTS: 121 COVID-19 patients were enrolled; 112 (92.6%) were admitted while nine (7.4%) were seen as outpatients. The median (IQR) age of patients was 41 (30–54) years; 72 (59.5%) were male. The median (IQR) reported days from hospital admission to recovery and to death were 10 (6–18) and 5.5 (3–9), respectively. Forty-four (36.4%) patients had at least one underlying condition. Of the 112 admissions, 17 (15.2%) went to ICU, of whom 14 (82.3%) died. At the end of follow-up, 93 (76.9%) recovered, 18 (14.9%) died, seven (5.8%) remained asymptomatic, and one (0.8%) remained ill. CONCLUSION: Three-quarters of all COVID-19 patients were less than 60 years, reflecting Africa's young population . High ICU admissions and mortality were observed.