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Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study
BACKGROUND: A prospective cohort study of the clinical presentations and management outcomes of laboratory-confirmed COVID-19 patients in the early months of the pandemic was performed at two hospitals in Dar es Salaam, Tanzania. METHODS: Between April 1 and May 31, 2020, laboratory-confirmed COVID-...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734168/ https://www.ncbi.nlm.nih.gov/pubmed/35721420 http://dx.doi.org/10.1016/j.ijregi.2021.12.010 |
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author | Mnyambwa, Nicholaus P. Lubinza, Clara Ngadaya, Esther Senkoro, Mbazi Kimaro, Godfather Kagaruki, Gibson B. Binagi, Stanley Malima, Amani Kazyoba, Paul Oriyo, Ndekya Mghamba, Janneth M. Fredrick, Aman Ramaiya, Kaushik Zumla, Alimuddin Jaffar, Shabbar Mfinanga, Sayoki G. |
author_facet | Mnyambwa, Nicholaus P. Lubinza, Clara Ngadaya, Esther Senkoro, Mbazi Kimaro, Godfather Kagaruki, Gibson B. Binagi, Stanley Malima, Amani Kazyoba, Paul Oriyo, Ndekya Mghamba, Janneth M. Fredrick, Aman Ramaiya, Kaushik Zumla, Alimuddin Jaffar, Shabbar Mfinanga, Sayoki G. |
author_sort | Mnyambwa, Nicholaus P. |
collection | PubMed |
description | BACKGROUND: A prospective cohort study of the clinical presentations and management outcomes of laboratory-confirmed COVID-19 patients in the early months of the pandemic was performed at two hospitals in Dar es Salaam, Tanzania. METHODS: Between April 1 and May 31, 2020, laboratory-confirmed COVID-19 patients seen at two tertiary facilities were consecutively enrolled in the study and followed up for 21 days. RESULTS: 121 COVID-19 patients were enrolled; 112 (92.6%) were admitted while nine (7.4%) were seen as outpatients. The median (IQR) age of patients was 41 (30–54) years; 72 (59.5%) were male. The median (IQR) reported days from hospital admission to recovery and to death were 10 (6–18) and 5.5 (3–9), respectively. Forty-four (36.4%) patients had at least one underlying condition. Of the 112 admissions, 17 (15.2%) went to ICU, of whom 14 (82.3%) died. At the end of follow-up, 93 (76.9%) recovered, 18 (14.9%) died, seven (5.8%) remained asymptomatic, and one (0.8%) remained ill. CONCLUSION: Three-quarters of all COVID-19 patients were less than 60 years, reflecting Africa's young population . High ICU admissions and mortality were observed. |
format | Online Article Text |
id | pubmed-8734168 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-87341682022-01-06 Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study Mnyambwa, Nicholaus P. Lubinza, Clara Ngadaya, Esther Senkoro, Mbazi Kimaro, Godfather Kagaruki, Gibson B. Binagi, Stanley Malima, Amani Kazyoba, Paul Oriyo, Ndekya Mghamba, Janneth M. Fredrick, Aman Ramaiya, Kaushik Zumla, Alimuddin Jaffar, Shabbar Mfinanga, Sayoki G. IJID Reg Coronavirus (COVID-19) Collection BACKGROUND: A prospective cohort study of the clinical presentations and management outcomes of laboratory-confirmed COVID-19 patients in the early months of the pandemic was performed at two hospitals in Dar es Salaam, Tanzania. METHODS: Between April 1 and May 31, 2020, laboratory-confirmed COVID-19 patients seen at two tertiary facilities were consecutively enrolled in the study and followed up for 21 days. RESULTS: 121 COVID-19 patients were enrolled; 112 (92.6%) were admitted while nine (7.4%) were seen as outpatients. The median (IQR) age of patients was 41 (30–54) years; 72 (59.5%) were male. The median (IQR) reported days from hospital admission to recovery and to death were 10 (6–18) and 5.5 (3–9), respectively. Forty-four (36.4%) patients had at least one underlying condition. Of the 112 admissions, 17 (15.2%) went to ICU, of whom 14 (82.3%) died. At the end of follow-up, 93 (76.9%) recovered, 18 (14.9%) died, seven (5.8%) remained asymptomatic, and one (0.8%) remained ill. CONCLUSION: Three-quarters of all COVID-19 patients were less than 60 years, reflecting Africa's young population . High ICU admissions and mortality were observed. Elsevier 2022-01-06 /pmc/articles/PMC8734168/ /pubmed/35721420 http://dx.doi.org/10.1016/j.ijregi.2021.12.010 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Coronavirus (COVID-19) Collection Mnyambwa, Nicholaus P. Lubinza, Clara Ngadaya, Esther Senkoro, Mbazi Kimaro, Godfather Kagaruki, Gibson B. Binagi, Stanley Malima, Amani Kazyoba, Paul Oriyo, Ndekya Mghamba, Janneth M. Fredrick, Aman Ramaiya, Kaushik Zumla, Alimuddin Jaffar, Shabbar Mfinanga, Sayoki G. Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study |
title | Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study |
title_full | Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study |
title_fullStr | Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study |
title_full_unstemmed | Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study |
title_short | Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study |
title_sort | clinical characteristics and outcomes of confirmed covid-19 patients in the early months of the pandemic in tanzania: a multicenter cohort study |
topic | Coronavirus (COVID-19) Collection |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734168/ https://www.ncbi.nlm.nih.gov/pubmed/35721420 http://dx.doi.org/10.1016/j.ijregi.2021.12.010 |
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