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Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study

BACKGROUND: A prospective cohort study of the clinical presentations and management outcomes of laboratory-confirmed COVID-19 patients in the early months of the pandemic was performed at two hospitals in Dar es Salaam, Tanzania. METHODS: Between April 1 and May 31, 2020, laboratory-confirmed COVID-...

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Autores principales: Mnyambwa, Nicholaus P., Lubinza, Clara, Ngadaya, Esther, Senkoro, Mbazi, Kimaro, Godfather, Kagaruki, Gibson B., Binagi, Stanley, Malima, Amani, Kazyoba, Paul, Oriyo, Ndekya, Mghamba, Janneth M., Fredrick, Aman, Ramaiya, Kaushik, Zumla, Alimuddin, Jaffar, Shabbar, Mfinanga, Sayoki G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734168/
https://www.ncbi.nlm.nih.gov/pubmed/35721420
http://dx.doi.org/10.1016/j.ijregi.2021.12.010
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author Mnyambwa, Nicholaus P.
Lubinza, Clara
Ngadaya, Esther
Senkoro, Mbazi
Kimaro, Godfather
Kagaruki, Gibson B.
Binagi, Stanley
Malima, Amani
Kazyoba, Paul
Oriyo, Ndekya
Mghamba, Janneth M.
Fredrick, Aman
Ramaiya, Kaushik
Zumla, Alimuddin
Jaffar, Shabbar
Mfinanga, Sayoki G.
author_facet Mnyambwa, Nicholaus P.
Lubinza, Clara
Ngadaya, Esther
Senkoro, Mbazi
Kimaro, Godfather
Kagaruki, Gibson B.
Binagi, Stanley
Malima, Amani
Kazyoba, Paul
Oriyo, Ndekya
Mghamba, Janneth M.
Fredrick, Aman
Ramaiya, Kaushik
Zumla, Alimuddin
Jaffar, Shabbar
Mfinanga, Sayoki G.
author_sort Mnyambwa, Nicholaus P.
collection PubMed
description BACKGROUND: A prospective cohort study of the clinical presentations and management outcomes of laboratory-confirmed COVID-19 patients in the early months of the pandemic was performed at two hospitals in Dar es Salaam, Tanzania. METHODS: Between April 1 and May 31, 2020, laboratory-confirmed COVID-19 patients seen at two tertiary facilities were consecutively enrolled in the study and followed up for 21 days. RESULTS: 121 COVID-19 patients were enrolled; 112 (92.6%) were admitted while nine (7.4%) were seen as outpatients. The median (IQR) age of patients was 41 (30–54) years; 72 (59.5%) were male. The median (IQR) reported days from hospital admission to recovery and to death were 10 (6–18) and 5.5 (3–9), respectively. Forty-four (36.4%) patients had at least one underlying condition. Of the 112 admissions, 17 (15.2%) went to ICU, of whom 14 (82.3%) died. At the end of follow-up, 93 (76.9%) recovered, 18 (14.9%) died, seven (5.8%) remained asymptomatic, and one (0.8%) remained ill. CONCLUSION: Three-quarters of all COVID-19 patients were less than 60 years, reflecting Africa's young population . High ICU admissions and mortality were observed.
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spelling pubmed-87341682022-01-06 Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study Mnyambwa, Nicholaus P. Lubinza, Clara Ngadaya, Esther Senkoro, Mbazi Kimaro, Godfather Kagaruki, Gibson B. Binagi, Stanley Malima, Amani Kazyoba, Paul Oriyo, Ndekya Mghamba, Janneth M. Fredrick, Aman Ramaiya, Kaushik Zumla, Alimuddin Jaffar, Shabbar Mfinanga, Sayoki G. IJID Reg Coronavirus (COVID-19) Collection BACKGROUND: A prospective cohort study of the clinical presentations and management outcomes of laboratory-confirmed COVID-19 patients in the early months of the pandemic was performed at two hospitals in Dar es Salaam, Tanzania. METHODS: Between April 1 and May 31, 2020, laboratory-confirmed COVID-19 patients seen at two tertiary facilities were consecutively enrolled in the study and followed up for 21 days. RESULTS: 121 COVID-19 patients were enrolled; 112 (92.6%) were admitted while nine (7.4%) were seen as outpatients. The median (IQR) age of patients was 41 (30–54) years; 72 (59.5%) were male. The median (IQR) reported days from hospital admission to recovery and to death were 10 (6–18) and 5.5 (3–9), respectively. Forty-four (36.4%) patients had at least one underlying condition. Of the 112 admissions, 17 (15.2%) went to ICU, of whom 14 (82.3%) died. At the end of follow-up, 93 (76.9%) recovered, 18 (14.9%) died, seven (5.8%) remained asymptomatic, and one (0.8%) remained ill. CONCLUSION: Three-quarters of all COVID-19 patients were less than 60 years, reflecting Africa's young population . High ICU admissions and mortality were observed. Elsevier 2022-01-06 /pmc/articles/PMC8734168/ /pubmed/35721420 http://dx.doi.org/10.1016/j.ijregi.2021.12.010 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Coronavirus (COVID-19) Collection
Mnyambwa, Nicholaus P.
Lubinza, Clara
Ngadaya, Esther
Senkoro, Mbazi
Kimaro, Godfather
Kagaruki, Gibson B.
Binagi, Stanley
Malima, Amani
Kazyoba, Paul
Oriyo, Ndekya
Mghamba, Janneth M.
Fredrick, Aman
Ramaiya, Kaushik
Zumla, Alimuddin
Jaffar, Shabbar
Mfinanga, Sayoki G.
Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study
title Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study
title_full Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study
title_fullStr Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study
title_full_unstemmed Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study
title_short Clinical characteristics and outcomes of confirmed COVID-19 patients in the early months of the pandemic in Tanzania: a multicenter cohort study
title_sort clinical characteristics and outcomes of confirmed covid-19 patients in the early months of the pandemic in tanzania: a multicenter cohort study
topic Coronavirus (COVID-19) Collection
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734168/
https://www.ncbi.nlm.nih.gov/pubmed/35721420
http://dx.doi.org/10.1016/j.ijregi.2021.12.010
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