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Non-parametric synergy modeling of chemical compounds with Gaussian processes

BACKGROUND: Understanding the synergetic and antagonistic effects of combinations of drugs and toxins is vital for many applications, including treatment of multifactorial diseases and ecotoxicological monitoring. Synergy is usually assessed by comparing the response of drug combinations to a predic...

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Detalles Bibliográficos
Autores principales:	Shapovalova, Yuliya, Heskes, Tom, Dijkstra, Tjeerd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734200/ https://www.ncbi.nlm.nih.gov/pubmed/34991440 http://dx.doi.org/10.1186/s12859-021-04508-7

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