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Evaluation of sexual dysfunction in gynecologic cancer survivors using DSM-5 diagnostic criteria
BACKGROUND: In gynecologic cancer survivors, female sexual dysfunction (FSD) remains under-investigated. We attempted to estimate the prevalence of FSD associated with distress in gynecologic cancer survivors using diagnostic and statistical manual of mental disorders fifth edition (DSM-5) diagnosti...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734329/ https://www.ncbi.nlm.nih.gov/pubmed/34986812 http://dx.doi.org/10.1186/s12905-021-01559-z |
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author | Lin, Hao Fu, Hung-Chun Wu, Chen-Hsuan Tsai, Yi-Jen Chou, Yin-Jou Shih, Chun-Ming Ou, Yu-Che |
author_facet | Lin, Hao Fu, Hung-Chun Wu, Chen-Hsuan Tsai, Yi-Jen Chou, Yin-Jou Shih, Chun-Ming Ou, Yu-Che |
author_sort | Lin, Hao |
collection | PubMed |
description | BACKGROUND: In gynecologic cancer survivors, female sexual dysfunction (FSD) remains under-investigated. We attempted to estimate the prevalence of FSD associated with distress in gynecologic cancer survivors using diagnostic and statistical manual of mental disorders fifth edition (DSM-5) diagnostic criteria and to identify women at risk for FSD. METHODS: We conducted a cross-sectional analysis of premenopausal women aged 20–50 with various gynecologic cancers at least one year after treatment between January 2017 and December 2019. Data of sociodemographics and physical conditions were collected via face-to-face interview during outpatient clinic visits. The domains we used to define FSD were based on DSM-5 diagnostic criteria. Statistical analysis was carried out using Student's t test, Chi-square test and multiple logistic regression. RESULTS: A total of 126 gynecologic cancer survivors with a mean age of 42.4 years were included for analysis and 55 of them (43.7%) were diagnosed as having FSD associated with distress based on DSM-5 criteria. More than half of women (65.1%) reported decreased sexual satisfaction after cancer treatment. According to DSM-5 definition, the most common female sexual disorders were sexual interest/arousal disorder (70.9%), followed by genitopelvic pain/penetration disorder (60.0%), and orgasmic disorder (20.0%). In multiple logistic regression model, endometrial cancer diagnosis was the only independent factor predicting less influence of cancer treatment on FSD (OR 0.370; 95% CI 0.160, 0.856). CONCLUSION: The first study to use DSM-5 criteria for estimation of FSD prevalence. This enables clinicians to identify which women are actually needed to seek medical help. A prevalence of 43.7% of FSD associated with distress was found in a group of gynecologic cancer survivors with the most common being sexual interest/arousal disorder. Endometrial cancer survivors were at low risk for developing FSD after treatment. |
format | Online Article Text |
id | pubmed-8734329 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-87343292022-01-07 Evaluation of sexual dysfunction in gynecologic cancer survivors using DSM-5 diagnostic criteria Lin, Hao Fu, Hung-Chun Wu, Chen-Hsuan Tsai, Yi-Jen Chou, Yin-Jou Shih, Chun-Ming Ou, Yu-Che BMC Womens Health Research BACKGROUND: In gynecologic cancer survivors, female sexual dysfunction (FSD) remains under-investigated. We attempted to estimate the prevalence of FSD associated with distress in gynecologic cancer survivors using diagnostic and statistical manual of mental disorders fifth edition (DSM-5) diagnostic criteria and to identify women at risk for FSD. METHODS: We conducted a cross-sectional analysis of premenopausal women aged 20–50 with various gynecologic cancers at least one year after treatment between January 2017 and December 2019. Data of sociodemographics and physical conditions were collected via face-to-face interview during outpatient clinic visits. The domains we used to define FSD were based on DSM-5 diagnostic criteria. Statistical analysis was carried out using Student's t test, Chi-square test and multiple logistic regression. RESULTS: A total of 126 gynecologic cancer survivors with a mean age of 42.4 years were included for analysis and 55 of them (43.7%) were diagnosed as having FSD associated with distress based on DSM-5 criteria. More than half of women (65.1%) reported decreased sexual satisfaction after cancer treatment. According to DSM-5 definition, the most common female sexual disorders were sexual interest/arousal disorder (70.9%), followed by genitopelvic pain/penetration disorder (60.0%), and orgasmic disorder (20.0%). In multiple logistic regression model, endometrial cancer diagnosis was the only independent factor predicting less influence of cancer treatment on FSD (OR 0.370; 95% CI 0.160, 0.856). CONCLUSION: The first study to use DSM-5 criteria for estimation of FSD prevalence. This enables clinicians to identify which women are actually needed to seek medical help. A prevalence of 43.7% of FSD associated with distress was found in a group of gynecologic cancer survivors with the most common being sexual interest/arousal disorder. Endometrial cancer survivors were at low risk for developing FSD after treatment. BioMed Central 2022-01-05 /pmc/articles/PMC8734329/ /pubmed/34986812 http://dx.doi.org/10.1186/s12905-021-01559-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Lin, Hao Fu, Hung-Chun Wu, Chen-Hsuan Tsai, Yi-Jen Chou, Yin-Jou Shih, Chun-Ming Ou, Yu-Che Evaluation of sexual dysfunction in gynecologic cancer survivors using DSM-5 diagnostic criteria |
title | Evaluation of sexual dysfunction in gynecologic cancer survivors using DSM-5 diagnostic criteria |
title_full | Evaluation of sexual dysfunction in gynecologic cancer survivors using DSM-5 diagnostic criteria |
title_fullStr | Evaluation of sexual dysfunction in gynecologic cancer survivors using DSM-5 diagnostic criteria |
title_full_unstemmed | Evaluation of sexual dysfunction in gynecologic cancer survivors using DSM-5 diagnostic criteria |
title_short | Evaluation of sexual dysfunction in gynecologic cancer survivors using DSM-5 diagnostic criteria |
title_sort | evaluation of sexual dysfunction in gynecologic cancer survivors using dsm-5 diagnostic criteria |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734329/ https://www.ncbi.nlm.nih.gov/pubmed/34986812 http://dx.doi.org/10.1186/s12905-021-01559-z |
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