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COX-2/sEH Dual Inhibitor PTUPB Alleviates CCl(4)-Induced Liver Fibrosis and Portal Hypertension

Background: 4-(5-phenyl-3-{3-[3-(4-trifluoromethylphenyl)-ureido]-propyl}-pyrazol-1-yl) -benzenesulfonamide (PTUPB), a dual cyclooxygenase-2 (COX-2)/soluble epoxide hydrolase (sEH) inhibitor, was found to alleviate renal, pulmonary fibrosis and liver injury. However, few is known about the effect of...

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Detalles Bibliográficos
Autores principales:	Zhao, Zhifeng, Zhang, Chihao, Lin, Jiayun, Zheng, Lei, Li, Hongjie, Qi, Xiaoliang, Huo, Haizhong, Lou, Xiaolou, Hammock, Bruce D., Hwang, Sung Hee, Bao, Yongyang, Luo, Meng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734593/ https://www.ncbi.nlm.nih.gov/pubmed/35004731 http://dx.doi.org/10.3389/fmed.2021.761517

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