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Sensitivity of eight types of ALK fusion variant to alectinib in ALK-transformed cells

Tyrosine kinase inhibitors of anaplastic lymphoma kinase (ALK-TKIs) including alectinib have been the standard therapy against ALK fusion gene-positive non–small cell lung cancers (NSCLCs). Many ALK fusion variants have been identified in NSCLCs, and the predominant variants are echinoderm microtubu...

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Detalles Bibliográficos
Autores principales:	Furugaki, Koh, Harada, Naoki, Yoshimura, Yasushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Pre-Clinical Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734629/ https://www.ncbi.nlm.nih.gov/pubmed/34520436 http://dx.doi.org/10.1097/CAD.0000000000001249

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