Treponema pallidum genome sequencing from six continents reveals variability in vaccine candidate genes and dominance of Nichols clade strains in Madagascar

In spite of its immutable susceptibility to penicillin, Treponema pallidum (T. pallidum) subsp. pallidum continues to cause millions of cases of syphilis each year worldwide, resulting in significant morbidity and mortality and underscoring the urgency of developing an effective vaccine to curtail t...

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Detalles Bibliográficos
Autores principales: Lieberman, Nicole A. P., Lin, Michelle J., Xie, Hong, Shrestha, Lasata, Nguyen, Tien, Huang, Meei-Li, Haynes, Austin M., Romeis, Emily, Wang, Qian-Qiu, Zhang, Rui-Li, Kou, Cai-Xia, Ciccarese, Giulia, Dal Conte, Ivano, Cusini, Marco, Drago, Francesco, Nakayama, Shu-ichi, Lee, Kenichi, Ohnishi, Makoto, Konda, Kelika A., Vargas, Silver K., Eguiluz, Maria, Caceres, Carlos F., Klausner, Jeffrey D., Mitjà, Oriol, Rompalo, Anne, Mulcahy, Fiona, Hook, Edward W., Lukehart, Sheila A., Casto, Amanda M., Roychoudhury, Pavitra, DiMaio, Frank, Giacani, Lorenzo, Greninger, Alexander L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735616/
https://www.ncbi.nlm.nih.gov/pubmed/34936652
http://dx.doi.org/10.1371/journal.pntd.0010063

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