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The rarA gene as part of an expanded RecFOR recombination pathway: Negative epistasis and synthetic lethality with ruvB, recG, and recQ

The RarA protein, homologous to human WRNIP1 and yeast MgsA, is a AAA(+) ATPase and one of the most highly conserved DNA repair proteins. With an apparent role in the repair of stalled or collapsed replication forks, the molecular function of this protein family remains obscure. Here, we demonstrate...

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Detalles Bibliográficos
Autores principales: Jain, Kanika, Wood, Elizabeth A., Cox, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735627/
https://www.ncbi.nlm.nih.gov/pubmed/34936656
http://dx.doi.org/10.1371/journal.pgen.1009972