Obstructive Constipation in Two Patients With Severe Osteogenesis Imperfecta and Acetabular Protrusio

Osteogenesis imperfecta (OI) is a rare genetic condition resulting in decreased bone density and bony deformity and a wide variety of extraskeletal manifestations. Acetabular protrusio and constipation are both commonly associated with OI. We present two cases of severe pelvic deformity resulting in mechanical colonic outlet obstruction, which were successfully treated with a colostomy. Colostomy as the definitive treatment of severe constipation in OI has not previously been reported in the literature.