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Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports

RATIONALE: Intraspinal gout tophus in the lumbar vertebral canal associated with gouty arthritis is rare. We present 2 cases with the first manifestations of a sequestrated intervertebral disc and an extradural tumor, and histopathologically proven to be gouty deposits in the lumbar vertebral canal....

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Autores principales: Wu, Zhiqiang, Liu, Chunhua, Dai, Kehui, Zheng, Chunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735772/
https://www.ncbi.nlm.nih.gov/pubmed/35029886
http://dx.doi.org/10.1097/MD.0000000000028418
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author Wu, Zhiqiang
Liu, Chunhua
Dai, Kehui
Zheng, Chunfeng
author_facet Wu, Zhiqiang
Liu, Chunhua
Dai, Kehui
Zheng, Chunfeng
author_sort Wu, Zhiqiang
collection PubMed
description RATIONALE: Intraspinal gout tophus in the lumbar vertebral canal associated with gouty arthritis is rare. We present 2 cases with the first manifestations of a sequestrated intervertebral disc and an extradural tumor, and histopathologically proven to be gouty deposits in the lumbar vertebral canal. PATIENT CONCERNS: The 2 patients presented with typical radiculopathy symptoms and a positive straight leg raise. In 1 case, there was weakness of the left toe extensors, with a positive left femoral nerve traction test. Additionally, the left patellar tendon reflex was weak. In the other patient who was unable to walk, there was a sensory deficit in the saddle distribution. DIAGNOSIS: Histopathological examination of the specimens taken from the operation confirmed the presence of gouty deposits. INTERVENTIONS: Posterior decompression was performed in these 2 cases, and chalky-white materials were identified in the lumbar vertebral canal. OUTCOMES: No evidence of neoplasm, infection, or synovial cyst was found. LESSONS: Definitive diagnosis of intraspinal extradural gout tophus, mimicking a sequestrated intervertebral disc or an extradural tumor, may be difficult. The initial suspicion of intraspinal gouty deposits, based on the diagnostic/management algorithm, may effectively avoid incorrect diagnosis via a less invasive procedure than explorative laminectomy.
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spelling pubmed-87357722022-01-11 Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports Wu, Zhiqiang Liu, Chunhua Dai, Kehui Zheng, Chunfeng Medicine (Baltimore) 4100 RATIONALE: Intraspinal gout tophus in the lumbar vertebral canal associated with gouty arthritis is rare. We present 2 cases with the first manifestations of a sequestrated intervertebral disc and an extradural tumor, and histopathologically proven to be gouty deposits in the lumbar vertebral canal. PATIENT CONCERNS: The 2 patients presented with typical radiculopathy symptoms and a positive straight leg raise. In 1 case, there was weakness of the left toe extensors, with a positive left femoral nerve traction test. Additionally, the left patellar tendon reflex was weak. In the other patient who was unable to walk, there was a sensory deficit in the saddle distribution. DIAGNOSIS: Histopathological examination of the specimens taken from the operation confirmed the presence of gouty deposits. INTERVENTIONS: Posterior decompression was performed in these 2 cases, and chalky-white materials were identified in the lumbar vertebral canal. OUTCOMES: No evidence of neoplasm, infection, or synovial cyst was found. LESSONS: Definitive diagnosis of intraspinal extradural gout tophus, mimicking a sequestrated intervertebral disc or an extradural tumor, may be difficult. The initial suspicion of intraspinal gouty deposits, based on the diagnostic/management algorithm, may effectively avoid incorrect diagnosis via a less invasive procedure than explorative laminectomy. Lippincott Williams & Wilkins 2022-01-07 /pmc/articles/PMC8735772/ /pubmed/35029886 http://dx.doi.org/10.1097/MD.0000000000028418 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/)
spellingShingle 4100
Wu, Zhiqiang
Liu, Chunhua
Dai, Kehui
Zheng, Chunfeng
Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports
title Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports
title_full Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports
title_fullStr Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports
title_full_unstemmed Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports
title_short Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports
title_sort intraspinal extradural gout tophus in the lumbar vertebral canal: case reports
topic 4100
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735772/
https://www.ncbi.nlm.nih.gov/pubmed/35029886
http://dx.doi.org/10.1097/MD.0000000000028418
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