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Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports
RATIONALE: Intraspinal gout tophus in the lumbar vertebral canal associated with gouty arthritis is rare. We present 2 cases with the first manifestations of a sequestrated intervertebral disc and an extradural tumor, and histopathologically proven to be gouty deposits in the lumbar vertebral canal....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735772/ https://www.ncbi.nlm.nih.gov/pubmed/35029886 http://dx.doi.org/10.1097/MD.0000000000028418 |
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author | Wu, Zhiqiang Liu, Chunhua Dai, Kehui Zheng, Chunfeng |
author_facet | Wu, Zhiqiang Liu, Chunhua Dai, Kehui Zheng, Chunfeng |
author_sort | Wu, Zhiqiang |
collection | PubMed |
description | RATIONALE: Intraspinal gout tophus in the lumbar vertebral canal associated with gouty arthritis is rare. We present 2 cases with the first manifestations of a sequestrated intervertebral disc and an extradural tumor, and histopathologically proven to be gouty deposits in the lumbar vertebral canal. PATIENT CONCERNS: The 2 patients presented with typical radiculopathy symptoms and a positive straight leg raise. In 1 case, there was weakness of the left toe extensors, with a positive left femoral nerve traction test. Additionally, the left patellar tendon reflex was weak. In the other patient who was unable to walk, there was a sensory deficit in the saddle distribution. DIAGNOSIS: Histopathological examination of the specimens taken from the operation confirmed the presence of gouty deposits. INTERVENTIONS: Posterior decompression was performed in these 2 cases, and chalky-white materials were identified in the lumbar vertebral canal. OUTCOMES: No evidence of neoplasm, infection, or synovial cyst was found. LESSONS: Definitive diagnosis of intraspinal extradural gout tophus, mimicking a sequestrated intervertebral disc or an extradural tumor, may be difficult. The initial suspicion of intraspinal gouty deposits, based on the diagnostic/management algorithm, may effectively avoid incorrect diagnosis via a less invasive procedure than explorative laminectomy. |
format | Online Article Text |
id | pubmed-8735772 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-87357722022-01-11 Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports Wu, Zhiqiang Liu, Chunhua Dai, Kehui Zheng, Chunfeng Medicine (Baltimore) 4100 RATIONALE: Intraspinal gout tophus in the lumbar vertebral canal associated with gouty arthritis is rare. We present 2 cases with the first manifestations of a sequestrated intervertebral disc and an extradural tumor, and histopathologically proven to be gouty deposits in the lumbar vertebral canal. PATIENT CONCERNS: The 2 patients presented with typical radiculopathy symptoms and a positive straight leg raise. In 1 case, there was weakness of the left toe extensors, with a positive left femoral nerve traction test. Additionally, the left patellar tendon reflex was weak. In the other patient who was unable to walk, there was a sensory deficit in the saddle distribution. DIAGNOSIS: Histopathological examination of the specimens taken from the operation confirmed the presence of gouty deposits. INTERVENTIONS: Posterior decompression was performed in these 2 cases, and chalky-white materials were identified in the lumbar vertebral canal. OUTCOMES: No evidence of neoplasm, infection, or synovial cyst was found. LESSONS: Definitive diagnosis of intraspinal extradural gout tophus, mimicking a sequestrated intervertebral disc or an extradural tumor, may be difficult. The initial suspicion of intraspinal gouty deposits, based on the diagnostic/management algorithm, may effectively avoid incorrect diagnosis via a less invasive procedure than explorative laminectomy. Lippincott Williams & Wilkins 2022-01-07 /pmc/articles/PMC8735772/ /pubmed/35029886 http://dx.doi.org/10.1097/MD.0000000000028418 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | 4100 Wu, Zhiqiang Liu, Chunhua Dai, Kehui Zheng, Chunfeng Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports |
title | Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports |
title_full | Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports |
title_fullStr | Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports |
title_full_unstemmed | Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports |
title_short | Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports |
title_sort | intraspinal extradural gout tophus in the lumbar vertebral canal: case reports |
topic | 4100 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735772/ https://www.ncbi.nlm.nih.gov/pubmed/35029886 http://dx.doi.org/10.1097/MD.0000000000028418 |
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