Cargando…

Flavonoids as tyrosinase inhibitors in in silico and in vitro models: basic framework of SAR using a statistical modelling approach

Flavonoids are widely distributed in plants and constitute the most common polyphenolic phytoconstituents in the human diet. In this study, the in vitro inhibitory activity of 44 different flavonoids (1–44) against mushroom tyrosinase was studied, and an in silico study and type of inhibition for th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jakimiuk, Katarzyna, Sari, Suat, Milewski, Robert, Supuran, Claudiu T., Şöhretoğlu, Didem, Tomczyk, Michał
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8735877/ https://www.ncbi.nlm.nih.gov/pubmed/34923888 http://dx.doi.org/10.1080/14756366.2021.2014832

Ejemplares similares

Reply letter to Dr. Wojtasek regarding: Oxidation of flavonoids by tyrosinase and by o-quinones–comment on "Flavonoids as tyrosinase inhibitors in in silico and in vitro models: basic framework of SAR using a statistical modelling approach” published by K. Jakimiuk, S. Sari, R. Milewski, C.T. Supuran, D. Söhretoglu, and M. Tomczyk (J Enzyme Inhib Med Chem 2022;37:427-436)
por: Tomczyk, Michał
Publicado: (2023)

Multiple biological effects of secondary metabolites of Ziziphus jujuba: isolation and mechanistic insights through in vitro and in silico studies
por: Şöhretoğlu, Didem, et al.
Publicado: (2022)

Flavonoids as inhibitors of human neutrophil elastase
por: Jakimiuk, Katarzyna, et al.
Publicado: (2021)

Oxidation of flavonoids by tyrosinase and by o-quinones–comment on "Flavonoids as tyrosinase inhibitors in in silico and in vitro models: basic framework of SAR using a statistical modelling approach” published by K. Jakimiuk, S. Sari, R. Milewski, C.T. Supuran, D. Şöhretoğlu, and M. Tomczyk (J Enzyme Inhib Med Chem 2022;37:427–436)
por: Wojtasek, Hubert
Publicado: (2023)

In Vitro Screening for Anti-Acetylcholinesterase and Antioxidant Activities of Hottonia palustris L. Extracts and Their Unusual Flavonoids
por: Strawa, Jakub W., et al.
Publicado: (2022)

Determination of Flavonoids in Selected Scleranthus Species and Their Anti-Collagenase and Antioxidant Potential
por: Jakimiuk, Katarzyna, et al.
Publicado: (2022)

Investigation of the Membrane Localization and Interaction of Selected Flavonoids by NMR and FTIR Spectroscopy
por: Kapral-Piotrowska, Justyna, et al.
Publicado: (2023)

Zapotin, a Polymethoxyflavone, with Potential Therapeutic Attributes
por: Strawa, Jakub W., et al.
Publicado: (2021)

Tyrosinase inhibitory activity of flavonoids from Artocarpus heterophyllous
por: Nguyen, Hai Xuan, et al.
Publicado: (2016)

Glycerolic Licorice Extracts as Active Cosmeceutical Ingredients: Extraction Optimization, Chemical Characterization, and Biological Activity
por: Ciganović, Petar, et al.
Publicado: (2019)

New Flavone C-Glycosides from Scleranthus perennis and Their Anti-Collagenase Activity
por: Jakimiuk, Katarzyna, et al.
Publicado: (2021)

Sanguiins—Promising Molecules with Broad Biological Potential
por: Gesek, Jakub, et al.
Publicado: (2021)

Comparative Evaluation of Phenolic Profile, Antioxidative and Cytotoxic Activities of Different Geranium Species
por: Şöhretoğlu, Didem, et al.
Publicado: (2017)

Immunomodulatory properties of triterpenes
por: Renda, Gülin, et al.
Publicado: (2021)

Tiliroside Combined with Anti-MUC1 Monoclonal Antibody as Promising Anti-Cancer Strategy in AGS Cancer Cells
por: Radziejewska, Iwona, et al.
Publicado: (2023)

Anti-Melanogenic Effects of Flavonoid Glycosides from Limonium tetragonum (Thunb.) Bullock via Inhibition of Tyrosinase and Tyrosinase-Related Proteins
por: Lee, Seul-Gi, et al.
Publicado: (2017)

Sulphonamides incorporating 1,3,5-triazine structural motifs show antioxidant, acetylcholinesterase, butyrylcholinesterase, and tyrosinase inhibitory profile
por: Lolak, Nabih, et al.
Publicado: (2020)

ReishiMax inhibits mTORC1/2 by activating AMPK and inhibiting IGFR/PI3K/Rheb in tumor cells
por: Sohretoglu, Didem, et al.
Publicado: (2019)

Optimization of Flavonoid Extraction in Dendrobium officinale Leaves and Their Inhibitory Effects on Tyrosinase Activity
por: Lu, Haixia, et al.
Publicado: (2019)

Molecular Simulation Study on the Interaction between Tyrosinase and Flavonoids from Sea Buckthorn
por: Li, Xiaofang, et al.
Publicado: (2021)

Synthesis of calix[4]azacrown substituted sulphonamides with antioxidant, acetylcholinesterase, butyrylcholinesterase, tyrosinase and carbonic anhydrase inhibitory action
por: Oguz, Mehmet, et al.
Publicado: (2020)

Functional in silico analysis of human tyrosinase and OCA1 associated mutations
por: Patel, Milan, et al.
Publicado: (2020)

Correlation between the Potency of Flavonoids on Mushroom Tyrosinase Inhibitory Activity and Melanin Synthesis in Melanocytes
por: Promden, Worrawat, et al.
Publicado: (2018)

Natural and synthetic flavonoid derivatives as new potential tyrosinase inhibitors: a systematic review
por: Obaid, Rami J., et al.
Publicado: (2021)

Promotion effects of flavonoids on browning induced by enzymatic oxidation of tyrosinase: structure–activity relationship
por: Lu, Yao, et al.
Publicado: (2021)

Insights on the Inhibitory Power of Flavonoids on Tyrosinase Activity: A Survey from 2016 to 2021
por: El-Nashar, Heba A. S., et al.
Publicado: (2021)

Bacterial Tyrosinase Inhibition, Hemolytic and Thrombolytic Screening, and In Silico Modeling of Rationally Designed Tosyl Piperazine-Engrafted Dithiocarbamate Derivatives
por: Zahoor, Ameer Fawad, et al.
Publicado: (2023)

Statistical dictionaries for hypothetical in silico model of the early-stage intermediate in protein folding
por: Kalinowska, Barbara, et al.
Publicado: (2015)

Tyrosinase inhibitory properties of phenylpropanoid glycosides and flavonoids from Teucrium polium L. var. gnaphalodes
por: Boghrati, Zahra, et al.
Publicado: (2016)

In vitro and in silico insights into tyrosinase inhibitors with (E)-benzylidene-1-indanone derivatives
por: Jung, Hee Jin, et al.
Publicado: (2019)

The Role of Anthocyanins, Deoxyanthocyanins and Pyranoanthocyanins on the Modulation of Tyrosinase Activity: An In Vitro and In Silico Approach
por: Correia, Patrícia, et al.
Publicado: (2021)

Elucidating the Role of Santalol as a Potent Inhibitor of Tyrosinase: In Vitro and In Silico Approaches
por: Ali, Nabeel, et al.
Publicado: (2022)

Melanin production by Pseudomonas sp. and in silico comparative analysis of tyrosinase gene sequences
por: Deepthi, Seelam Siva, et al.
Publicado: (2021)

New Polymethoxyflavones from Hottonia palustris Evoke DNA Biosynthesis-Inhibitory Activity in An Oral Squamous Carcinoma (SCC-25) Cell Line
por: Strawa, Jakub W., et al.
Publicado: (2022)

Evaluation of caffeine as inhibitor against collagenase, elastase and tyrosinase using in silico and in vitro approach
por: Eun Lee, Kyung, et al.
Publicado: (2019)

In silico and in vitro insights into tyrosinase inhibitors with a 2-thioxooxazoline-4-one template
por: Choi, Inkyu, et al.
Publicado: (2020)

Synthesis, in silico modelling, and in vitro biological evaluation of substituted pyrazole derivatives as potential anti-skin cancer, anti-tyrosinase, and antioxidant agents
por: Boateng, Samuel T., et al.
Publicado: (2023)

Wound Healing Properties of Jasione montana Extracts and Their Main Secondary Metabolites
por: Juszczak, Aleksandra Maria, et al.
Publicado: (2022)

An in-silico framework for modeling optimal control of neural systems
por: Rueckauer, Bodo, et al.
Publicado: (2023)

Basic statistics
por: Thomas, Seemon
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_bk88lbs6a8kmf41vvboplm0vc0