Cargando…

Carrier-free prodrug nanoparticles based on dasatinib and cisplatin for efficient antitumor in vivo

Carrier-free drug self-delivery systems consisting of amphiphilic drug-drug conjugate (ADDC) with well-defined structure and nanoscale features have drawn much attention in tumor drug delivery. Herein, we report a simple and effective strategy to prepare ADDC using derivatives of cisplatin (CP) and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Lu, Xu, Jiaxi, Xie, Zheng, Song, Faquan, Wang, Xin, Tang, Rupei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shenyang Pharmaceutical University 2021
Materias:	Original Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8737405/ https://www.ncbi.nlm.nih.gov/pubmed/35027952 http://dx.doi.org/10.1016/j.ajps.2021.08.001

Ejemplares similares

Preclinical development of carrier-free prodrug nanoparticles for enhanced antitumor therapeutic potential with less toxicity
por: Shim, Man Kyu, et al.
Publicado: (2022)

Carrier-free nanoparticles of camptothecin prodrug for chemo-photothermal therapy: the making, in vitro and in vivo testing
por: Ao, Mingtao, et al.
Publicado: (2021)

Antitumor effects of Dasatinib on laryngeal squamous cell carcinoma in vivo and in vitro
por: Song, Yan, et al.
Publicado: (2013)

Research Progress of Carrier-Free Antitumor Nanoparticles Based on Phytochemicals
por: Jiang, Siliang, et al.
Publicado: (2021)

Dynamic crosslinked polymeric nano-prodrugs for highly selective synergistic chemotherapy
por: Wang, Shi, et al.
Publicado: (2022)

Dual-Drug Nanosystem: Etoposide Prodrug and Cisplatin Coloaded Nanostructured Lipid Carriers for Lung Cancer Therapy
por: Du, Min, et al.
Publicado: (2022)

Pure redox-sensitive paclitaxel–maleimide prodrug nanoparticles: Endogenous albumin-induced size switching and improved antitumor efficiency
por: Lou, Xinyu, et al.
Publicado: (2021)

Structure-Based Rational Design of Prodrugs To Enable Their Combination with Polymeric Nanoparticle Delivery Platforms for Enhanced Antitumor Efficacy**
por: Wang, Hangxiang, et al.
Publicado: (2014)

pH-triggered dynamic erosive small molecule chlorambucil nano-prodrugs mediate robust oral chemotherapy
por: Liu, Xin, et al.
Publicado: (2023)

Prodrug-based nano-delivery strategy to improve the antitumor ability of carboplatin in vivo and in vitro
por: Lang, Tingting, et al.
Publicado: (2021)

Probing the fluorination effect on the self-assembly characteristics, in vivo fate and antitumor efficacy of paclitaxel prodrug nanoassemblies
por: Wang, Xin, et al.
Publicado: (2021)

Antitumor activity of the bioreductive prodrug 3-(2-nitrophenyl) propionic acid-paclitaxel nanoparticles (NPPA-PTX NPs) on MDA-MB-231 cells: in vitro and in vivo
por: Duan, Xiao-Chuan, et al.
Publicado: (2018)

Dasatinib enhances antitumor activity of paclitaxel in ovarian cancer through Src signaling
por: XIAO, JUAN, et al.
Publicado: (2015)

A Nanostrategy for Efficient Imaging‐Guided Antitumor Therapy through a Stimuli‐Responsive Branched Polymeric Prodrug
por: Cai, Hao, et al.
Publicado: (2020)

Biocompatible Nanoparticles as a Platform for Enhancing Antitumor Efficacy of Cisplatin–Tetradrine Combination
por: Liu, Fangcen, et al.
Publicado: (2021)

Polylactide-tethered prodrugs in polymeric nanoparticles as reliable nanomedicines for the efficient eradication of patient-derived hepatocellular carcinoma
por: Wang, Hangxiang, et al.
Publicado: (2018)

In vivo, ex vivo and in vitro dasatinib activity in chronic lymphocytic leukemia
por: Giannopoulos, Krzysztof, et al.
Publicado: (2021)

Glutathione‐Responsive Nanoparticles of Camptothecin Prodrug for Cancer Therapy
por: Zhang, Lingpu, et al.
Publicado: (2022)

Detoxifying Antitumoral Drugs via Nanoconjugation: The Case of Gold Nanoparticles and Cisplatin
por: Comenge, Joan, et al.
Publicado: (2012)

Combination Chemotherapy of Lung Cancer – Co-Delivery of Docetaxel Prodrug and Cisplatin Using Aptamer-Decorated Lipid–Polymer Hybrid Nanoparticles
por: Wu, Ruifeng, et al.
Publicado: (2020)

Co-drug delivery of regorafenib and cisplatin with amphiphilic copolymer nanoparticles: enhanced in vivo antitumor cancer therapy in nursing care
por: Zhou, Zhe
Publicado: (2020)

Glycosystems in nanotechnology: Gold glyconanoparticles as carrier for anti-HIV prodrugs
por: Chiodo, Fabrizio, et al.
Publicado: (2014)

Engineering of lipid prodrug-based, hyaluronic acid-decorated nanostructured lipid carriers platform for 5-fluorouracil and cisplatin combination gastric cancer therapy
por: Qu, Chun-Ying, et al.
Publicado: (2015)

Adapting decarbonylation chemistry for the development of prodrugs capable of in vivo delivery of carbon monoxide utilizing sweeteners as carrier molecules
por: De La Cruz, Ladie Kimberly, et al.
Publicado: (2021)

Dasatinib-Loaded Erythrocytes Trigger Apoptosis in Untreated Chronic Myelogenous Leukemic Cells: A Cellular Reservoir Participating in Dasatinib Efficiency
por: Airiau, Kelly, et al.
Publicado: (2018)

Caffeine citrate enhanced cisplatin antitumor effects in osteosarcoma and fibrosarcoma in vitro and in vivo
por: Abe, Kensaku, et al.
Publicado: (2019)

Editorial: The role of platinum-based antitumor prodrugs in medicinal inorganic chemistry
por: Margiotta, Nicola, et al.
Publicado: (2023)

A Dasatinib-Induced Chylothorax Persisting After the Discontinuation of Dasatinib
por: Bradt, Nicolas, et al.
Publicado: (2022)

Desymmetrization of pibrentasvir for efficient prodrug synthesis
por: Voight, Eric A., et al.
Publicado: (2021)

Octreotide-periplocymarin conjugate prodrug for improving targetability and anti-tumor efficiency: synthesis, in vitro and in vivo evaluation
por: Zhang, Hui-Yun, et al.
Publicado: (2016)

Co-delivery of a tumor microenvironment-responsive disulfiram prodrug and CuO(2) nanoparticles for efficient cancer treatment
por: Cheng, Fen-Ting, et al.
Publicado: (2023)

The synergistic antitumor effect of cinobufagin and cisplatin in human osteosarcoma cell line in vitro and in vivo
por: Dai, Guo, et al.
Publicado: (2017)

Leukaemic cells expressing ETV6::FRK are sensitive to dasatinib in vivo
por: Mayumi, Azusa, et al.
Publicado: (2023)

The Role of Bystander Effects in the Antitumor Activity of the Hypoxia-Activated Prodrug PR-104
por: Foehrenbacher, Annika, et al.
Publicado: (2013)

TMTP1-Modified, Tumor Microenvironment Responsive Nanoparticles Co-Deliver Cisplatin and Paclitaxel Prodrugs for Effective Cervical Cancer Therapy
por: Jiang, Guiying, et al.
Publicado: (2021)

Dasatinib-Related Chylothorax
por: Huang, Yen-Min, et al.
Publicado: (2015)

DASATINIB-RELATED CHYLOTHORAX
por: Young, Katherine, et al.
Publicado: (2019)

Regulating Glucose Metabolism with Prodrug Nanoparticles for Promoting Photoimmunotherapy of Pancreatic Cancer
por: Sun, Fang, et al.
Publicado: (2021)

In vitro and in vivo evaluation of macromolecular prodrug GC-FUA based nanoparticle for hepatocellular carcinoma chemotherapy
por: Huang, Can, et al.
Publicado: (2017)

Design of pH-sensitive methotrexate prodrug-targeted curcumin nanoparticles for efficient dual-drug delivery and combination cancer therapy
por: Xie, Jiajiang, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_q1qad3gvssvq8c8sd5i2b1hrhl