Vulnerability to Meningococcal Disease in Immunodeficiency Due to a Novel Pathogenic Missense Variant in NFKB1

NF-κB1 deficiency is suggested to be the most common cause of common variable immunodeficiency (CVID). NFKB1 encodes for the p105 precursor protein of NF-κB1, which is converted into the active transcriptional subunit p50 through proteasomal processing of its C-terminal half upon stimulation and is...

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Detalles Bibliográficos
Autores principales: Anim, Manfred, Sogkas, Georgios, Schmidt, Gunnar, Dubrowinskaja, Natalia, Witte, Torsten, Schmidt, Reinhold Ernst, Atschekzei, Faranaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738076/
https://www.ncbi.nlm.nih.gov/pubmed/35003082
http://dx.doi.org/10.3389/fimmu.2021.767188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738076/
https://www.ncbi.nlm.nih.gov/pubmed/35003082
http://dx.doi.org/10.3389/fimmu.2021.767188

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