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Early life exposure to house dust mite allergen prevents experimental allergic asthma requiring mitochondrial H(2)O(2)
Immune tolerance to allergens in early-life decreases the risk for asthma in later life. Here we show establishment of stable airway tolerance to the allergen, house dust mite (HDM), by exposing newborn mice repeatedly to a low dose of the allergen. Lung dendritic cells (DCs) from tolerized mice ind...
Autores principales: | Yuan, Huijuan, Chen, Jie, Hu, Sanmei, Oriss, Timothy B., Kale, Sagar Laxman, Das, Sudipta, Nouraie, Seyed M., Ray, Prabir, Ray, Anuradha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738138/ https://www.ncbi.nlm.nih.gov/pubmed/34580428 http://dx.doi.org/10.1038/s41385-021-00458-8 |
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