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The Alternative Complement Pathway Is Activated Without a Corresponding Terminal Pathway Activation in Patients With Heart Failure

OBJECTIVE: Dysregulation of the complement system has been described in patients with heart failure (HF). However, data on the alternative pathway are scarce and it is unknown if levels of factor B (FB) and the C3 convertase C3bBbP are elevated in these patients. We hypothesized that plasma levels o...

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Detalles Bibliográficos
Autores principales:	Holt, Margrethe Flesvig, Michelsen, Annika E., Shahini, Negar, Bjørkelund, Elisabeth, Bendz, Christina Holt, Massey, Richard J., Schjalm, Camilla, Halvorsen, Bente, Broch, Kaspar, Ueland, Thor, Gullestad, Lars, Nilsson, Per H., Aukrust, Pål, Mollnes, Tom Eirik, Louwe, Mieke C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738166/ https://www.ncbi.nlm.nih.gov/pubmed/35003128 http://dx.doi.org/10.3389/fimmu.2021.800978

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