Cargando…
The Prognostic Role of MYC Structural Variants Identified by NGS and FISH in Multiple Myeloma
PURPOSE: Structural variants (SV) of the MYC gene region are common in multiple myeloma and influence disease progression. However, the prognostic significance of different MYC SVs in multiple myeloma has not been clearly established. EXPERIMENTAL DESIGN: We conducted a retrospective study of multip...
Autores principales: | Sharma, Neeraj, Smadbeck, James B., Abdallah, Nadine, Zepeda-Mendoza, Cinthya, Binder, Moritz, Pearce, Kathryn E., Asmann, Yan W., Peterson, Jess F., Ketterling, Rhett P., Greipp, Patricia T., Bergsagel, P. Leif, Rajkumar, S. Vincent, Kumar, Shaji K., Baughn, Linda B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738776/ https://www.ncbi.nlm.nih.gov/pubmed/34233962 http://dx.doi.org/10.1158/1078-0432.CCR-21-0005 |
Ejemplares similares
-
Elucidating a false-negative MYC break-apart fluorescence in situ hybridization probe study by next-generation sequencing in a patient with high-grade B-cell lymphoma with IGH/MYC and IGH/BCL2 rearrangements
por: Peterson, Jess F., et al.
Publicado: (2019) -
Increased complexity of t(11;14) rearrangements in plasma cell neoplasms compared with mantle cell lymphoma
por: Dalland, Joanna C., et al.
Publicado: (2021) -
Mate pair sequencing outperforms fluorescence in situ hybridization in the genomic characterization of multiple myeloma
por: Smadbeck, James, et al.
Publicado: (2019) -
Myeloid malignancies with 5q and 7q deletions are associated with extreme genomic complexity, biallelic TP53 variants, and very poor prognosis
por: Pitel, Beth A., et al.
Publicado: (2021) -
MYC break-apart FISH probe set reveals frequent unbalanced patterns of uncertain significance when evaluating aggressive B-cell lymphoma
por: Gagnon, Marie-France, et al.
Publicado: (2021)