Cargando…

Integrative analysis reveals methylenetetrahydrofolate dehydrogenase 1-like as an independent shared diagnostic and prognostic biomarker in five different human cancers

Background: Defects in methylenetetrahydrofolate dehydrogenase 1-like (MTHFD1L) expression have earlier been examined in only a few human cancers. Objectives: Multi-omics profiling of MTHFD1L as a shared biomarker in distinct subtypes of human cancers. Methods: In the current study, for the multi-om...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sial, Nuzhat, Rehman, Jalil Ur, Saeed, Saba, Ahmad, Mukhtiar, Hameed, Yasir, Atif, Muhammad, Rehman, Abdul, Asif, Rizwan, Ahmed, Hamad, Hussain, Muhammad Safdar, Khan, Muhammad Rashid, Ambreen, Atifa, Ambreen, Ayesha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2022
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738869/ https://www.ncbi.nlm.nih.gov/pubmed/34908119 http://dx.doi.org/10.1042/BSR20211783

Ejemplares similares

Multi-Omics Analysis Identified TMED2 as a Shared Potential Biomarker in Six Subtypes of Human Cancer
por: Sial, Nuzhat, et al.
Publicado: (2021)

CTHRC1 expression is a novel shared diagnostic and prognostic biomarker of survival in six different human cancer subtypes
por: Sial, Nuzhat, et al.
Publicado: (2021)

Fishing for vaccines against Vibrio cholerae using in silico pan-proteomic reverse vaccinology approach
por: Rashid, Muhammad I., et al.
Publicado: (2019)

Synthesis, enzyme inhibitory kinetics mechanism and computational study of N-(4-methoxyphenethyl)-N-(substituted)-4-methylbenzenesulfonamides as novel therapeutic agents for Alzheimer’s disease
por: Abbasi, Muhammad Athar, et al.
Publicado: (2018)

Gene Ontology Capsule GAN: an improved architecture for protein function prediction
por: Mansoor, Musadaq, et al.
Publicado: (2022)

Model-based in silico analysis of the PI3K/Akt pathway: the elucidation of cross-talk between diabetes and breast cancer
por: Rehman, Sammia, et al.
Publicado: (2018)

Diagnosis of dengue virus infection using spectroscopic images and deep learning
por: Hassan, Mehdi, et al.
Publicado: (2022)

Computational analysis of Cyclin D1 gene SNPs and association with breast cancer
por: Aftab, Ayesha, et al.
Publicado: (2021)

BCD-WERT: a novel approach for breast cancer detection using whale optimization based efficient features and extremely randomized tree algorithm
por: Abbas, Shafaq, et al.
Publicado: (2021)

Survival, growth, behavior, hematology and serum biochemistry of mice under different concentrations of orally administered amorphous silica nanoparticle
por: Ismail, Amna, et al.
Publicado: (2023)

Green Synthesis of Silver Nanoparticles (AgNPs), Structural Characterization, and their Antibacterial Potential
por: Asif, Muhammad, et al.
Publicado: (2022)

Does human papillomavirus cause human colorectal cancer? Applying Bradford Hill criteria postulates
por: Usman, Muhammad, et al.
Publicado: (2020)

An analytical study on the identification of N-linked glycosylation sites using machine learning model
por: Akmal, Muhammad Aizaz, et al.
Publicado: (2022)

Domain analyses of Usher syndrome causing Clarin-1 and GPR98 protein models
por: Khan, Sehrish Haider, et al.
Publicado: (2014)

Toxicity of Melaleuca alternifolia essential oil to the mitochondrion and NAD(+)/NADH dehydrogenase in Tribolium confusum
por: Liao, Min, et al.
Publicado: (2018)

Runaway pacemaker
por: Gul, Ambreen, et al.
Publicado: (2019)

A high-performance, hardware-based deep learning system for disease diagnosis
por: Siddique, Ali, et al.
Publicado: (2022)

Screening of high-risk deleterious missense variations in the CYP1B1 gene implicated in the pathogenesis of primary congenital glaucoma: A comprehensive in silico approach
por: Shahid, Muhammad, et al.
Publicado: (2022)

Comparative analysis of machine learning approaches to analyze and predict the COVID-19 outbreak
por: Naeem, Muhammad, et al.
Publicado: (2021)

Kinship identification using age transformation and Siamese network
por: Abbas, Arshad, et al.
Publicado: (2022)

Theoretical and Experimental Insights of Benzimidazole Catalyzed by the Epoxy–Acrylic Acid Reaction
por: Saif, Muhammad Jawwad, et al.
Publicado: (2022)

ZnSe-rGO nanocomposites as photocatalysts for purification of textile dye contaminated water: A green approach to use wastewater for maize cultivation
por: Zahra, Mishal, et al.
Publicado: (2023)

Mirizzi’s syndrome masquerading as cholangiocarcinoma: a case report
por: Khan, Muhammad Rizwan, et al.
Publicado: (2012)

Genome-wide identification of alcohol dehydrogenase (ADH) gene family under waterlogging stress in wheat (Triticum aestivum)
por: Shen, Changwei, et al.
Publicado: (2021)

Construction of a competing endogenous RNA network to analyse glucose-6-phosphate dehydrogenase dysregulation in hepatocellular carcinoma
por: Wang, Pengyu, et al.
Publicado: (2022)

Phylogenetic comparison between Type IX Secretion System (T9SS) protein components suggests evidence of horizontal gene transfer
por: Emrizal, Reeki, et al.
Publicado: (2020)

Growth Response in Oryctolagus cuniculus to Selenium Toxicity Exposure Ameliorated with Vitamin E
por: Rehman, Rukhshanda, et al.
Publicado: (2022)

Engineering of phenylalanine dehydrogenase from Thermoactinomyces intermedius for the production of a novel homoglutamate
por: Tariq, Muhammad, et al.
Publicado: (2022)

Can We Convert Genotype Sequences Into Images for Cases/Controls Classification?
por: Muneeb, Muhammad, et al.
Publicado: (2022)

Graph data science and machine learning for the detection of COVID-19 infection from symptoms
por: Alqaissi, Eman, et al.
Publicado: (2023)

Seed priming with growth regulators modulates production, physiology and antioxidant defense of Indian squash (Praecitrullus fistulosus) under semi-arid conditions
por: Qamar, Rafi, et al.
Publicado: (2022)

Identification and In Silico Analysis of a Homozygous Nonsense Variant in TGM1 Gene Segregating with Congenital Ichthyosis in a Consanguineous Family
por: Almazroea, Abdulhadi, et al.
Publicado: (2023)

Sharing data, sharing methods, sharing science.
por: Pantano, Sergio
Publicado: (2021)

Psychosocial implications of blindness and low vision in students of a school for children with blindness
por: Ishtiaq, Rizwan, et al.
Publicado: (2016)

Drug discovery of anticancer drugs targeting methylenetetrahydrofolate dehydrogenase 2
por: Asai, Ayumu, et al.
Publicado: (2018)

Crystal structure of Thermus thermophilus methylenetetrahydrofolate dehydrogenase and determinants of thermostability
por: Maiello, Fernando, et al.
Publicado: (2020)

The catalytic mechanism of the mitochondrial methylenetetrahydrofolate dehydrogenase/cyclohydrolase (MTHFD2)
por: Zhao, Li Na, et al.
Publicado: (2022)

DHU-Pred: accurate prediction of dihydrouridine sites using position and composition variant features on diverse classifiers
por: Suleman, Muhammad Taseer, et al.
Publicado: (2022)

Towards survival prediction of cancer patients using medical images
por: Ul Haq, Nazeef, et al.
Publicado: (2022)

Glecaprevir and Maraviroc are high-affinity inhibitors of SARS-CoV-2 main protease: possible implication in COVID-19 therapy
por: Shamsi, Anas, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_07bhb7h6m47919db57f83jjshm