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Relationship between DNA mismatch repair and CRISPR/Cas9-mediated knock-in in the bovine β-casein gene locus

OBJECTIVE: Efficient gene editing technology is critical for successful knock-in in domestic animals. RAD51 recombinase (RAD51) gene plays an important role in strand invasion during homologous recombination (HR) in mammals, and is regulated by checkpoint kinase 1 (CHK1) and CHK2 genes, which are up...

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Detalles Bibliográficos
Autores principales:	Kim, Seung-Yeon, Kim, Ga-Yeon, You, Hyeong-Ju, Kang, Man-Jong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Animal Bioscience 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738927/ https://www.ncbi.nlm.nih.gov/pubmed/34293843 http://dx.doi.org/10.5713/ab.21.0117

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