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Inhibition of IKKβ/NF-κB signaling facilitates tendinopathy healing by rejuvenating inflamm-aging induced tendon-derived stem/progenitor cell senescence

Degenerative rotator cuff tendinopathy (RCT) is a chronic tendon disease caused by degeneration and inflammation, which often affects the elderly population. Mesenchymal stem cell senescence is generally recognized as an important pathophysiological mechanism in many age-related skeletal diseases. H...

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Detalles Bibliográficos
Autores principales: Wang, Chongyang, Zhou, Zhekun, Song, Wei, Cai, Zhuochang, Ding, Zhenyu, Chen, Daoyun, Xia, Fangfang, He, Yaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738957/
https://www.ncbi.nlm.nih.gov/pubmed/35036066
http://dx.doi.org/10.1016/j.omtn.2021.12.026