(R)-Baclofen [(R)-4-amino-3-(4-chloro­phen­yl)butanoic acid]

This article provides the first single-crystal XRD-based structure of enanti­opure (R)-baclofen (form C), C(10)H(12)ClNO(2), without any co-crystallized substances. In the enanti­opure title compound, the mol­ecules arrange themselves in an ortho­rhom­bic crystal structure (space group P2(1)2(1)2(1)...

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Detalles Bibliográficos
Autores principales: Belov, Feodor, Villinger, Alexander, von Langermann, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739196/
https://www.ncbi.nlm.nih.gov/pubmed/35079419
http://dx.doi.org/10.1107/S2056989021012809
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author Belov, Feodor
Villinger, Alexander
von Langermann, Jan
author_facet Belov, Feodor
Villinger, Alexander
von Langermann, Jan
author_sort Belov, Feodor
collection PubMed
description This article provides the first single-crystal XRD-based structure of enanti­opure (R)-baclofen (form C), C(10)H(12)ClNO(2), without any co-crystallized substances. In the enanti­opure title compound, the mol­ecules arrange themselves in an ortho­rhom­bic crystal structure (space group P2(1)2(1)2(1)). In the crystal, strong hydrogen bonds and C—H⋯Cl bonds inter­connect the zwitterionic mol­ecules.
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spelling pubmed-87391962022-01-24 (R)-Baclofen [(R)-4-amino-3-(4-chloro­phen­yl)butanoic acid] Belov, Feodor Villinger, Alexander von Langermann, Jan Acta Crystallogr E Crystallogr Commun Research Communications This article provides the first single-crystal XRD-based structure of enanti­opure (R)-baclofen (form C), C(10)H(12)ClNO(2), without any co-crystallized substances. In the enanti­opure title compound, the mol­ecules arrange themselves in an ortho­rhom­bic crystal structure (space group P2(1)2(1)2(1)). In the crystal, strong hydrogen bonds and C—H⋯Cl bonds inter­connect the zwitterionic mol­ecules. International Union of Crystallography 2022-01-01 /pmc/articles/PMC8739196/ /pubmed/35079419 http://dx.doi.org/10.1107/S2056989021012809 Text en © Belov et al. 2022 https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Research Communications
Belov, Feodor
Villinger, Alexander
von Langermann, Jan
(R)-Baclofen [(R)-4-amino-3-(4-chloro­phen­yl)butanoic acid]
title (R)-Baclofen [(R)-4-amino-3-(4-chloro­phen­yl)butanoic acid]
title_full (R)-Baclofen [(R)-4-amino-3-(4-chloro­phen­yl)butanoic acid]
title_fullStr (R)-Baclofen [(R)-4-amino-3-(4-chloro­phen­yl)butanoic acid]
title_full_unstemmed (R)-Baclofen [(R)-4-amino-3-(4-chloro­phen­yl)butanoic acid]
title_short (R)-Baclofen [(R)-4-amino-3-(4-chloro­phen­yl)butanoic acid]
title_sort (r)-baclofen [(r)-4-amino-3-(4-chloro­phen­yl)butanoic acid]
topic Research Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739196/
https://www.ncbi.nlm.nih.gov/pubmed/35079419
http://dx.doi.org/10.1107/S2056989021012809
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