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Case Report: Opposite Effects of BRAF Inhibition on Closely Related Clonal Myeloid Disorders

Langerhans cell histiocytosis (LCH) commonly co-occurs with additional myeloid malignancies. The introduction of targeted therapies, blocking “driver” mutations (e.g., BRAF V600E), enabled long-term remission in patients with LCH. The effect of BRAF inhibition on the course and the prognosis of co-e...

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Detalles Bibliográficos
Autores principales:	Hostettler, Katrin E., Casañas Quintana, Elisa, Tamm, Michael, Savic Prince, Spasenija, Sommer, Gregor, Chen, Wei-Chih, Nordmann, Thierry Michael, Lundberg, Pontus, Stehle, Gregor Thomas, Daikeler, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739218/ https://www.ncbi.nlm.nih.gov/pubmed/35004300 http://dx.doi.org/10.3389/fonc.2021.779523

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