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Inactivation of PI3K/Akt promotes the odontoblastic differentiation and suppresses the stemness with autophagic flux in dental pulp cells

BACKGROUND/PURPOSE: Autophagy is involved in controlling differentiation of various cell types. The present study aimed to investigate the mechanism related to autophagy in regulating odontogenic differentiation of dental pulp cells. MATERIALS AND METHODS: Human dental pulp cells (HDPCs) were cultur...

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Detalles Bibliográficos
Autores principales: Park, Sam Young, Cho, Heui Seung, Chung, Kyung Hwun, Lee, Bin Na, Kim, Sun Hun, Kim, Won Jae, Jung, Ji Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Dental Sciences of the Republic of China 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739242/
https://www.ncbi.nlm.nih.gov/pubmed/35028032
http://dx.doi.org/10.1016/j.jds.2021.05.013