Generation of human long-lived plasma cells by developmentally regulated epigenetic imprinting

Antibody secreting cells (ASCs) circulate after vaccination and infection and migrate to the BM where a subset known as long-lived plasma cells (LLPCs) persists and secrete antibodies for a lifetime. The mechanisms by which circulating ASCs become LLPCs are not well elucidated. Here, we show that hu...

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Detalles Bibliográficos
Autores principales: Joyner, Chester J, Ley, Ariel M, Nguyen, Doan C, Ali, Mohammad, Corrado, Alessia, Tipton, Christopher, Scharer, Christopher D, Mi, Tian, Woodruff, Matthew C, Hom, Jennifer, Boss, Jeremy M, Duan, Meixue, Gibson, Greg, Roberts, Danielle, Andrews, Joel, Lonial, Sagar, Sanz, Inaki, Lee, F Eun-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739272/
https://www.ncbi.nlm.nih.gov/pubmed/34952892
http://dx.doi.org/10.26508/lsa.202101285

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