Metabolite profiling reveals a connection between aldehyde dehydrogenase 1A3 and GABA metabolism in breast cancer metastasis

INTRODUCTION: Aldehyde dehydrogenase 1A3 (ALDH1A3) is a cancer stem cell (CSC) marker and in breast cancer it is associated with triple-negative/basal-like subtypes and aggressive disease. Studies on the mechanisms of ALDH1A3 in cancer have primarily focused on gene expression changes induced by the...

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Detalles Bibliográficos
Autores principales: Dahn, Margaret L., Walsh, Hayley R., Dean, Cheryl A., Giacomantonio, Michael A., Fernando, Wasundara, Murphy, J Patrick, Walker, Olivia L., Wasson, Marie-Claire D., Gujar, Shashi, Pinto, Devanand M., Marcato, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739322/
https://www.ncbi.nlm.nih.gov/pubmed/34989902
http://dx.doi.org/10.1007/s11306-021-01864-6

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