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FUS driven circCNOT6L biogenesis in mouse and human spermatozoa supports zygote development
Circular RNA (circRNA) biogenesis requires a backsplicing reaction, promoted by inverted repeats in cis-flanking sequences and trans factors, such as RNA-binding proteins (RBPs). Among these, FUS plays a key role. During spermatogenesis and sperm maturation along the epididymis such a molecular mech...
Autores principales: | Chioccarelli, Teresa, Falco, Geppino, Cappetta, Donato, De Angelis, Antonella, Roberto, Luca, Addeo, Martina, Ragusa, Marco, Barbagallo, Davide, Berrino, Liberato, Purrello, Michele, Ambrosino, Concetta, Cobellis, Gilda, Pierantoni, Riccardo, Chianese, Rosanna, Manfrevola, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739325/ https://www.ncbi.nlm.nih.gov/pubmed/34936029 http://dx.doi.org/10.1007/s00018-021-04054-8 |
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