Impact of booster vaccination on the control of COVID-19 Delta wave in the context of waning immunity: application to France in the winter 2021/22

Europe has experienced a large COVID-19 wave caused by the Delta variant in winter 2021/22. Using mathematical models applied to Metropolitan France, we find that boosters administered to ≥ 65, ≥ 50 or ≥ 18 year-olds may reduce the hospitalisation peak by 25%, 36% and 43% respectively, with a delay...

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Autores principales: Bosetti, Paolo, Tran Kiem, Cécile, Andronico, Alessio, Paireau, Juliette, Levy-Bruhl, Daniel, Alter, Lise, Fontanet, Arnaud, Cauchemez, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2022
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739339/
https://www.ncbi.nlm.nih.gov/pubmed/34991778
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.1.2101125
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author Bosetti, Paolo
Tran Kiem, Cécile
Andronico, Alessio
Paireau, Juliette
Levy-Bruhl, Daniel
Alter, Lise
Fontanet, Arnaud
Cauchemez, Simon
author_facet Bosetti, Paolo
Tran Kiem, Cécile
Andronico, Alessio
Paireau, Juliette
Levy-Bruhl, Daniel
Alter, Lise
Fontanet, Arnaud
Cauchemez, Simon
author_sort Bosetti, Paolo
collection PubMed
description Europe has experienced a large COVID-19 wave caused by the Delta variant in winter 2021/22. Using mathematical models applied to Metropolitan France, we find that boosters administered to ≥ 65, ≥ 50 or ≥ 18 year-olds may reduce the hospitalisation peak by 25%, 36% and 43% respectively, with a delay of 5 months between second and third dose. A 10% reduction in transmission rates might further reduce it by 41%, indicating that even small increases in protective behaviours may be critical to mitigate the wave.
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spelling pubmed-87393392022-02-07 Impact of booster vaccination on the control of COVID-19 Delta wave in the context of waning immunity: application to France in the winter 2021/22 Bosetti, Paolo Tran Kiem, Cécile Andronico, Alessio Paireau, Juliette Levy-Bruhl, Daniel Alter, Lise Fontanet, Arnaud Cauchemez, Simon Euro Surveill Rapid Communication Europe has experienced a large COVID-19 wave caused by the Delta variant in winter 2021/22. Using mathematical models applied to Metropolitan France, we find that boosters administered to ≥ 65, ≥ 50 or ≥ 18 year-olds may reduce the hospitalisation peak by 25%, 36% and 43% respectively, with a delay of 5 months between second and third dose. A 10% reduction in transmission rates might further reduce it by 41%, indicating that even small increases in protective behaviours may be critical to mitigate the wave. European Centre for Disease Prevention and Control (ECDC) 2022-01-06 /pmc/articles/PMC8739339/ /pubmed/34991778 http://dx.doi.org/10.2807/1560-7917.ES.2022.27.1.2101125 Text en This article is copyright of the authors or their affiliated institutions, 2022. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Bosetti, Paolo
Tran Kiem, Cécile
Andronico, Alessio
Paireau, Juliette
Levy-Bruhl, Daniel
Alter, Lise
Fontanet, Arnaud
Cauchemez, Simon
Impact of booster vaccination on the control of COVID-19 Delta wave in the context of waning immunity: application to France in the winter 2021/22
title Impact of booster vaccination on the control of COVID-19 Delta wave in the context of waning immunity: application to France in the winter 2021/22
title_full Impact of booster vaccination on the control of COVID-19 Delta wave in the context of waning immunity: application to France in the winter 2021/22
title_fullStr Impact of booster vaccination on the control of COVID-19 Delta wave in the context of waning immunity: application to France in the winter 2021/22
title_full_unstemmed Impact of booster vaccination on the control of COVID-19 Delta wave in the context of waning immunity: application to France in the winter 2021/22
title_short Impact of booster vaccination on the control of COVID-19 Delta wave in the context of waning immunity: application to France in the winter 2021/22
title_sort impact of booster vaccination on the control of covid-19 delta wave in the context of waning immunity: application to france in the winter 2021/22
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739339/
https://www.ncbi.nlm.nih.gov/pubmed/34991778
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.1.2101125
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