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SARS-CoV-2 Omicron spike glycoprotein receptor binding domain exhibits super-binder ability with ACE2 but not convalescent monoclonal antibody

SARS-CoV-2, the causative virus for COVID-19 has now super-mutated into the Omicron (Om) variant. On its spike (S) glycoprotein alone, more than 30 substitutions have been characterized with 15 within the receptor binding domain (RBD); It therefore calls to question the transmissibility and antibody...

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Detalles Bibliográficos
Autores principales: Omotuyi, Olaposi, Olubiyi, Olujide, Nash, Oyekanmi, Afolabi, Elizabeth, Oyinloye, Babatunji, Fatumo, Segun, Femi-Oyewo, Mbang, Bogoro, Suleiman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739363/
https://www.ncbi.nlm.nih.gov/pubmed/35066447
http://dx.doi.org/10.1016/j.compbiomed.2022.105226