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Intratumor expanded T cell clones can be non-sentinel lymph node derived in breast cancer revealed by single-cell immune profiling

BACKGROUND: Sentinel lymph nodes (LNs) are regarded as key immune surveillance sites in cancer wherein mature dendritic cells present tumor-derived antigens to prime and activate T cells, which then migrate to the tumor site. However, it is unclear whether the tumor-specific T cells can be elicited...

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Detalles Bibliográficos
Autores principales:	Jiao, Shiping, Xiong, Qing, Yan, Meisi, Zhan, Xiaolu, Yang, Zhenhuang, Peng, Cheng, Sun, Beicheng, Pang, Da, Liu, Tong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Clinical/Translational Cancer Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739441/ https://www.ncbi.nlm.nih.gov/pubmed/34992092 http://dx.doi.org/10.1136/jitc-2021-003325

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