Cargando…
Device-Based Enrichment of Knee Joint Synovial Cells to Drive MSC Chondrogenesis Without Prior Culture Expansion In Vitro: A Step Closer to 1-Stage Orthopaedic Procedures
BACKGROUND: Synovial fluid (SF) mesenchymal stem cells (MSCs) are derived from the synovial membrane and have cartilage repair potential. Their current use in clinical practice is largely exploratory. As their numbers tend to be small, therapeutic procedures using MSCs typically require culture expa...
Autores principales: | Altaie, Ala, Baboolal, Thomas G., Wall, Owen, Pandit, Hemant, Jones, Elena, McGonagle, Dennis |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739599/ https://www.ncbi.nlm.nih.gov/pubmed/34779670 http://dx.doi.org/10.1177/03635465211055164 |
Ejemplares similares
-
Gene Expression Signatures of Synovial Fluid Multipotent Stromal Cells in Advanced Knee Osteoarthritis and Following Knee Joint Distraction
por: Sanjurjo-Rodriguez, Clara, et al.
Publicado: (2020) -
A Novel Arthroscopic Technique for Intraoperative Mobilization of Synovial Mesenchymal Stem Cells
por: Baboolal, Thomas G., et al.
Publicado: (2018) -
Synovial fluid hyaluronan mediates MSC attachment to cartilage, a potential novel mechanism contributing to cartilage repair in osteoarthritis using knee joint distraction
por: Baboolal, Thomas G, et al.
Publicado: (2016) -
NSAIDS inhibit in vitro MSC chondrogenesis but not osteogenesis: implications for mechanism of bone formation inhibition in man
por: Pountos, Ippokratis, et al.
Publicado: (2011) -
Cytokine “fine tuning” of enthesis tissue homeostasis as a pointer to spondyloarthritis pathogenesis with a focus on relevant TNF and IL-17 targeted therapies
por: Russell, Tobias, et al.
Publicado: (2021)