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Role of Fcγ receptors in HER2-targeted breast cancer therapy

Several therapeutic monoclonal antibodies (mAbs), including those targeting epidermal growth factor receptor, human epidermal growth factor receptor 2 (HER2), and CD20, mediate fragment crystallizable gamma receptor (FcγR)–dependent activities as part of their mechanism of action. These activities i...

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Detalles Bibliográficos
Autores principales: Musolino, Antonino, Gradishar, William J, Rugo, Hope S, Nordstrom, Jeffrey L, Rock, Edwin P, Arnaldez, Fernanda, Pegram, Mark D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739678/
https://www.ncbi.nlm.nih.gov/pubmed/34992090
http://dx.doi.org/10.1136/jitc-2021-003171