Myxopyronin B inhibits growth of a Fidaxomicin-resistant Clostridioides difficile isolate and interferes with toxin synthesis

The anaerobic, gastrointestinal pathogen Clostridioides difficile can cause severe forms of enterocolitis which is mainly mediated by the toxins it produces. The RNA polymerase inhibitor Fidaxomicin is the current gold standard for the therapy of C. difficile infections due to several beneficial fea...

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Detalles Bibliográficos
Autores principales: Brauer, Madita, Herrmann, Jennifer, Zühlke, Daniela, Müller, Rolf, Riedel, Katharina, Sievers, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739712/
https://www.ncbi.nlm.nih.gov/pubmed/34991700
http://dx.doi.org/10.1186/s13099-021-00475-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739712/
https://www.ncbi.nlm.nih.gov/pubmed/34991700
http://dx.doi.org/10.1186/s13099-021-00475-9

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