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Migration and phenotype switching of macrophages at early-phase of bone-formation by secretomes from bone marrow derived mesenchymal stem cells using rat calvaria bone defect model

BACKGROUND/PURPOSE: Conditioned media of cultured mesenchymal stem cells (MSCs) contain numerous kinds of secretomes such as cytokines and chemokines. We previously reported that conditioned media of bone marrow-derived MSCs (MSC-CM) promote bone formation. Recently, macrophage phenotype switching f...

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Detalles Bibliográficos
Autores principales: Katagiri, Wataru, Takeuchi, Ryoko, Saito, Naoaki, Suda, Daisuke, Kobayashi, Tadaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Dental Sciences of the Republic of China 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739749/
https://www.ncbi.nlm.nih.gov/pubmed/35028066
http://dx.doi.org/10.1016/j.jds.2021.08.012

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