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Hyaluronidase and pH Dual-Responsive Nanoparticles for Targeted Breast Cancer Stem Cells

pH-responsive and CD44 receptor-mediated targeted nanoparticles for eliminating cancer stem cells (CSCs) were developed based on complexes of PEG-poly(β-amino ester) (PEG-PBAE) micelles (PPM) coated with hyaluronic acid (HA) (HA-coated PPM complex, or HPPMc). Thioridazine (Thz) was loaded into HPPMc...

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Detalles Bibliográficos
Autores principales: Li, Weinan, Zhang, Xiaoyu, Nan, Yang, Jia, Li, Sun, Jialin, Zhang, Lina, Wang, Yanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739758/
https://www.ncbi.nlm.nih.gov/pubmed/35004281
http://dx.doi.org/10.3389/fonc.2021.760423

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