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1.5 Tesla Magnetic Resonance Imaging Features of Canine Intracranial Intra-axial Hematomas

The differentiation of solitary intra-axial hematomas from hemorrhagic neoplasms based on their magnetic resonance imaging (MRI) features is challenging. The treatment and prognosis for these two disease entities are vastly different and distinction between them is often based on MRI findings alone....

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Autores principales: Whitlock, James, Holdsworth, Andrew, Morales, Carles, Garosi, Laurent, Carrera, Inés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739912/
https://www.ncbi.nlm.nih.gov/pubmed/35004926
http://dx.doi.org/10.3389/fvets.2021.778320
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author Whitlock, James
Holdsworth, Andrew
Morales, Carles
Garosi, Laurent
Carrera, Inés
author_facet Whitlock, James
Holdsworth, Andrew
Morales, Carles
Garosi, Laurent
Carrera, Inés
author_sort Whitlock, James
collection PubMed
description The differentiation of solitary intra-axial hematomas from hemorrhagic neoplasms based on their magnetic resonance imaging (MRI) features is challenging. The treatment and prognosis for these two disease entities are vastly different and distinction between them is often based on MRI findings alone. The aim of this study was to describe the 1.5 tesla MRI features of canine intra-axial hematomas and correlate these findings with the evolution of hemorrhages described in human brains. Retrospective evaluation of patient details, clinical signs, and MRI findings of dogs with intra-axial hematomas that were histopathologically confirmed or determined via repeat MRI study and/or resolution of neurological signs. Ten dogs met the inclusion criteria. All 10 hematoma lesions were determined to be 2–7 days in age. On MRI, all 10 hemorrhagic lesions were comprised of two distinct regions; a relatively thin T1-weighted (T1W), T2-weighted (T2W) and gradient echo (GRE) hypointense (9/10) peripheral border region and a large central region that was heterogenous but predominantly T1W, T2W and GRE hyperintense (8/10). The peripheral border region was complete in its integrity in all 10 cases on T2W and GRE sequences. Contrast enhancement was present in (6/10) hematoma lesions and was always peripheral in nature with no evidence of central enhancement associated with any of the lesions. An intra-axial hematoma should be suspected in solitary hemorrhagic space occupying lesions that have a complete hypointense peripheral rim, elicit a peripheral contrast enhancement pattern, and display the expected temporal pattern of hematoma evolution.
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spelling pubmed-87399122022-01-08 1.5 Tesla Magnetic Resonance Imaging Features of Canine Intracranial Intra-axial Hematomas Whitlock, James Holdsworth, Andrew Morales, Carles Garosi, Laurent Carrera, Inés Front Vet Sci Veterinary Science The differentiation of solitary intra-axial hematomas from hemorrhagic neoplasms based on their magnetic resonance imaging (MRI) features is challenging. The treatment and prognosis for these two disease entities are vastly different and distinction between them is often based on MRI findings alone. The aim of this study was to describe the 1.5 tesla MRI features of canine intra-axial hematomas and correlate these findings with the evolution of hemorrhages described in human brains. Retrospective evaluation of patient details, clinical signs, and MRI findings of dogs with intra-axial hematomas that were histopathologically confirmed or determined via repeat MRI study and/or resolution of neurological signs. Ten dogs met the inclusion criteria. All 10 hematoma lesions were determined to be 2–7 days in age. On MRI, all 10 hemorrhagic lesions were comprised of two distinct regions; a relatively thin T1-weighted (T1W), T2-weighted (T2W) and gradient echo (GRE) hypointense (9/10) peripheral border region and a large central region that was heterogenous but predominantly T1W, T2W and GRE hyperintense (8/10). The peripheral border region was complete in its integrity in all 10 cases on T2W and GRE sequences. Contrast enhancement was present in (6/10) hematoma lesions and was always peripheral in nature with no evidence of central enhancement associated with any of the lesions. An intra-axial hematoma should be suspected in solitary hemorrhagic space occupying lesions that have a complete hypointense peripheral rim, elicit a peripheral contrast enhancement pattern, and display the expected temporal pattern of hematoma evolution. Frontiers Media S.A. 2021-12-24 /pmc/articles/PMC8739912/ /pubmed/35004926 http://dx.doi.org/10.3389/fvets.2021.778320 Text en Copyright © 2021 Whitlock, Holdsworth, Morales, Garosi and Carrera. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Whitlock, James
Holdsworth, Andrew
Morales, Carles
Garosi, Laurent
Carrera, Inés
1.5 Tesla Magnetic Resonance Imaging Features of Canine Intracranial Intra-axial Hematomas
title 1.5 Tesla Magnetic Resonance Imaging Features of Canine Intracranial Intra-axial Hematomas
title_full 1.5 Tesla Magnetic Resonance Imaging Features of Canine Intracranial Intra-axial Hematomas
title_fullStr 1.5 Tesla Magnetic Resonance Imaging Features of Canine Intracranial Intra-axial Hematomas
title_full_unstemmed 1.5 Tesla Magnetic Resonance Imaging Features of Canine Intracranial Intra-axial Hematomas
title_short 1.5 Tesla Magnetic Resonance Imaging Features of Canine Intracranial Intra-axial Hematomas
title_sort 1.5 tesla magnetic resonance imaging features of canine intracranial intra-axial hematomas
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8739912/
https://www.ncbi.nlm.nih.gov/pubmed/35004926
http://dx.doi.org/10.3389/fvets.2021.778320
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