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Transient Receptor Potential Cation Channel Subfamily V Member 4 Mediates Pyroptosis in Chronic Obstructive Pulmonary Disease

TRPV4, a calcium permeable cation selective channel, was found to be involved in chronic obstructive pulmonary disease (COPD) through releasing ATP and IL-1β. Pyroptosis, a newly discovered pro-inflammatory cell death, was induced by cigarette smoke (CS) in airway epithelial cells (AECs). More recen...

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Detalles Bibliográficos
Autores principales: Rao, Yafei, Gai, Xiaoyan, Xiong, Jing, Le, Yanqing, Sun, Yongchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740047/
https://www.ncbi.nlm.nih.gov/pubmed/35002766
http://dx.doi.org/10.3389/fphys.2021.783891