Molecular Basis of Selective Cytokine Signaling Inhibition by Antibodies Targeting a Shared Receptor

Interleukin-1 (IL-1) family cytokines are potent mediators of inflammation, acting to coordinate local and systemic immune responses to a wide range of stimuli. Aberrant signaling by IL-1 family cytokine members, however, is linked to myriad inflammatory syndromes, autoimmune conditions and cancers....

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Detalles Bibliográficos
Autores principales: Fields, James K., Kihn, Kyle, Birkedal, Gabriel S., Klontz, Erik H., Sjöström, Kjell, Günther, Sebastian, Beadenkopf, Robert, Forsberg, Göran, Liberg, David, Snyder, Greg A., Deredge, Daniel, Sundberg, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740070/
https://www.ncbi.nlm.nih.gov/pubmed/35003094
http://dx.doi.org/10.3389/fimmu.2021.779100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740070/
https://www.ncbi.nlm.nih.gov/pubmed/35003094
http://dx.doi.org/10.3389/fimmu.2021.779100

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