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Molecular Basis of Selective Cytokine Signaling Inhibition by Antibodies Targeting a Shared Receptor

Interleukin-1 (IL-1) family cytokines are potent mediators of inflammation, acting to coordinate local and systemic immune responses to a wide range of stimuli. Aberrant signaling by IL-1 family cytokine members, however, is linked to myriad inflammatory syndromes, autoimmune conditions and cancers....

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Detalles Bibliográficos
Autores principales:	Fields, James K., Kihn, Kyle, Birkedal, Gabriel S., Klontz, Erik H., Sjöström, Kjell, Günther, Sebastian, Beadenkopf, Robert, Forsberg, Göran, Liberg, David, Snyder, Greg A., Deredge, Daniel, Sundberg, Eric J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740070/ https://www.ncbi.nlm.nih.gov/pubmed/35003094 http://dx.doi.org/10.3389/fimmu.2021.779100

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