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Synergistic effects of methyl 2-cyano-3,11-dioxo-18beta-olean-1,-12-dien-30-oate and erlotinib on erlotinib-resistant non-small cell lung cancer cells

Non-small cell lung cancer (NSCLC) is often characterized by an underlying mutation in the epidermal growth factor receptor (EGFR), contributing to aggressive metastatic disease. Methyl 2-cyano-3,11-dioxo-18beta-olean-1,12-dien-30-oate (CDODA-Me), a glycyrrhetinic acid derivative, reportedly improve...

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Detalles Bibliográficos
Autores principales: Nottingham, Ebony, Mazzio, Elizabeth, Surapaneni, Sunil Kumar, Kutlehria, Shallu, Mondal, Arindam, Badisa, Ramesh, Safe, Stephen, Rishi, Arun K., Singh, Mandip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740161/
https://www.ncbi.nlm.nih.gov/pubmed/35028186
http://dx.doi.org/10.1016/j.jpha.2021.06.002

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