Cargando…

LCK and CD3E Orchestrate the Tumor Microenvironment and Promote Immunotherapy Response and Survival of Muscle-Invasive Bladder Cancer Patients

Background: Studies have demonstrated the significance of multiple biomarkers for bladder cancer. Here, we attempt to present biomarkers potentially predictive of the prognosis and immunotherapy response of muscle-invasive bladder cancer (MIBC). Method: Immune and stromal scores were calculated for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Xiaonan, Liao, Xinyang, Nie, Ling, Lin, Tianhai, Xu, Hang, Yang, Lu, Shen, Bairong, Qiu, Shi, Ai, Jianzhong, Wei, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740181/ https://www.ncbi.nlm.nih.gov/pubmed/35004669 http://dx.doi.org/10.3389/fcell.2021.748280

Ejemplares similares

How the Discovery of the CD4/CD8-p56(lck) Complexes Changed Immunology and Immunotherapy
por: Rudd, Christopher E.
Publicado: (2021)

A Novel Immune-Gene Pair Signature Revealing the Tumor Microenvironment Features and Immunotherapy Prognosis of Muscle-Invasive Bladder Cancer
por: Zheng, Xiaonan, et al.
Publicado: (2021)

New insights into the Lck-NF-κB signaling pathway
por: Zhang, Jing, et al.
Publicado: (2023)

Long Noncoding RNAs as Orchestrators of CD4(+) T-Cell Fate
por: Liu, Chang, et al.
Publicado: (2022)

Endoplasmic Reticulum Stress and Tumor Microenvironment in Bladder Cancer: The Missing Link
por: Nie, Zhenyu, et al.
Publicado: (2021)

Multi-Omics Characterization of Tumor Microenvironment Heterogeneity and Immunotherapy Resistance Through Cell States–Based Subtyping in Bladder Cancer
por: Hu, Rixin, et al.
Publicado: (2022)

Towards Immunotherapy-Induced Normalization of the Tumor Microenvironment
por: Melo, Vinicio, et al.
Publicado: (2022)

Cooperative Interaction of Nck and Lck Orchestrates Optimal TCR Signaling
por: Hartl, Frederike A., et al.
Publicado: (2021)

Potential Strategies to Improve the Effectiveness of Drug Therapy by Changing Factors Related to Tumor Microenvironment
por: Cao, Dehong, et al.
Publicado: (2021)

Glycolysis in tumor microenvironment as a target to improve cancer immunotherapy
por: Xiao, Chu, et al.
Publicado: (2022)

Ferroptosis Patterns and Tumor Microenvironment Infiltration Characterization in Bladder Cancer
por: Xia, Qi-Dong, et al.
Publicado: (2022)

TCR-Induced Tyrosine Phosphorylation at Tyr270 of SUMO Protease SENP1 by Lck Modulates SENP1 Enzyme Activity and Specificity
por: Li, Yun-Yi, et al.
Publicado: (2022)

Editorial: Immune modulation in tumor microenvironment: New perspectives for cancer immunotherapy
por: Deng, Zimu, et al.
Publicado: (2023)

Gemcitabine-Resistant Biomarkers in Bladder Cancer are Associated with Tumor-Immune Microenvironment
por: Song, Yuxuan, et al.
Publicado: (2022)

Tumor‐associated macrophages promote bladder tumor growth through PI3K/AKT signal induced by collagen
por: Qiu, Shi, et al.
Publicado: (2019)

Non-immune Cell Components in the Gastrointestinal Tumor Microenvironment Influencing Tumor Immunotherapy
por: Li, Zhengshuo, et al.
Publicado: (2021)

The Identification of the Metabolism Subtypes of Skin Cutaneous Melanoma Associated With the Tumor Microenvironment and the Immunotherapy
por: Yang, Ronghua, et al.
Publicado: (2021)

Expression Patterns of Glycosylation Regulators Define Tumor Microenvironment and Immunotherapy in Gastric Cancer
por: Li, Fang, et al.
Publicado: (2022)

Orchestration of Immunological Synapse Assembly by Vesicular Trafficking
por: Onnis, Anna, et al.
Publicado: (2019)

Identification of Immune-Related Subtypes and Characterization of Tumor Microenvironment Infiltration in Bladder Cancer
por: Huang, Mengjia, et al.
Publicado: (2021)

Editorial: The Gut Microbiota Orchestrates the Neuronal-Immune System
por: Brun, Paola, et al.
Publicado: (2021)

Circular RNAs: Their Role in the Pathogenesis and Orchestration of Breast Cancer
por: He, Xiao, et al.
Publicado: (2021)

Hippo-Yap Pathway Orchestrates Neural Crest Ontogenesis
por: Zhao, Xiaolei, et al.
Publicado: (2021)

CD93 Correlates With Immune Infiltration and Impacts Patient Immunotherapy Efficacy: A Pan-Cancer Analysis
por: Zhang, Zerui, et al.
Publicado: (2022)

The Pan-Cancer Crosstalk Between the EFNA Family and Tumor Microenvironment for Prognosis and Immunotherapy of Gastric Cancer
por: Xie, Rongrong, et al.
Publicado: (2022)

Editorial: Thy1/CD90 Surface Glycoprotein: Sensor of Microenvironment?
por: Felley-Bosco, Emanuela, et al.
Publicado: (2019)

TNF Family–Based Signature Predicts Prognosis, Tumor Microenvironment, and Molecular Subtypes in Bladder Carcinoma
por: Li, Huihuang, et al.
Publicado: (2022)

Dynamic Changes in Myofibroblasts Affect the Carcinogenesis and Prognosis of Bladder Cancer Associated With Tumor Microenvironment Remodeling
por: Du, YiHeng, et al.
Publicado: (2022)

Chemical Decorations of “MARs” Residents in Orchestrating Eukaryotic Gene Regulation
por: Roychowdhury, Tanaya, et al.
Publicado: (2020)

Mitochondrial Fission and Mitophagy Reciprocally Orchestrate Cardiac Fibroblasts Activation
por: Gao, Qing-Yuan, et al.
Publicado: (2021)

Deciphering the Intercellular Communication Network of Peripartum Decidua that Orchestrates Delivery
por: Huang, Jingrui, et al.
Publicado: (2021)

Characterization of Molecular Heterogeneity Associated With Tumor Microenvironment in Clear Cell Renal Cell Carcinoma to Aid Immunotherapy
por: Zhong, Weimin, et al.
Publicado: (2021)

Multi-Omics Analysis of Novel Signature for Immunotherapy Response and Tumor Microenvironment Regulation Patterns in Urothelial Cancer
por: Chu, Guangdi, et al.
Publicado: (2021)

Fundamentals to therapeutics: Epigenetic modulation of CD8(+) T Cell exhaustion in the tumor microenvironment
por: Blake, Maja K., et al.
Publicado: (2023)

DNA Methylation Modification Map to Predict Tumor Molecular Subtypes and Efficacy of Immunotherapy in Bladder Cancer
por: Ye, Fangdie, et al.
Publicado: (2021)

Emerging Roles of the Intraflagellar Transport System in the Orchestration of Cellular Degradation Pathways
por: Finetti, Francesca, et al.
Publicado: (2019)

Retraction: Mitochondrial fission and mitophagy reciprocally orchestrate cardiac fibroblasts activation
Publicado: (2022)

The role of RNA-binding proteins in orchestrating germline development in Caenorhabditis elegans
por: Albarqi, Mennatallah M. Y., et al.
Publicado: (2023)

Behind the scenes: How RNA orchestrates the epigenetic regulation of gene expression
por: Mangiavacchi, Arianna, et al.
Publicado: (2023)

Dual effects of radiotherapy on tumor microenvironment and its contribution towards the development of resistance to immunotherapy in gastrointestinal and thoracic cancers
por: Zhao, Deyao, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_tkh1gl1f2us5enrjbv155h0d07