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Integrated Lymphopenia Analysis in Younger and Older Patients With Multiple Sclerosis Treated With Cladribine Tablets
Cladribine tablets (CladT) preferentially reduce B and T lymphocyte levels. As aging is associated with a decline in immune function, the effect of CladT on lymphocyte levels may differ by age. This post hoc analysis combined data from the Phase 3 CLARITY, CLARITY Extension, and ORACLE-MS studies to...
Autores principales: | Giovannoni, Gavin, Coyle, Patricia K., Vermersch, Patrick, Walker, Bryan, Aldridge, Julie, Nolting, Axel, Galazka, Andrew, Lemieux, Caroline, Leist, Thomas P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740297/ https://www.ncbi.nlm.nih.gov/pubmed/35003076 http://dx.doi.org/10.3389/fimmu.2021.763433 |
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