Dysregulated B cell differentiation towards antibody-secreting cells in neuromyelitis optica spectrum disorder

BACKGROUND: Anti-aquaporin 4 (AQP4) antibody (AQP4-Ab) is involved in the pathogenesis of neuromyelitis optica spectrum disorder (NMOSD). However, the mechanism involved in AQP4-Ab production remains unclear. METHODS: We analyzed the immunophenotypes of patients with NMOSD and other neuroinflammator...

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Detalles Bibliográficos
Autores principales: Hoshino, Yasunobu, Noto, Daisuke, Sano, Shuhei, Tomizawa, Yuji, Yokoyama, Kazumasa, Hattori, Nobutaka, Miyake, Sachiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740356/
https://www.ncbi.nlm.nih.gov/pubmed/34991631
http://dx.doi.org/10.1186/s12974-021-02375-w

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