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Computerized cognitive training in people with depression: a protocol for a systematic review and meta-analysis

BACKGROUND: People with depression often present with concurrent cognitive impairment. Computerized cognitive training (CCT) is a safe and efficacious strategy to maintain or enhance cognitive performance in a range of clinical populations. However, its efficacy in people with depression and how it...

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Autores principales: Lampit, Amit, Launder, Nathalie H., Minkov, Ruth, Rollini, Alice, Davey, Christopher G., Finke, Carsten, Lautenschlager, Nicola T., Gavelin, Hanna Malmberg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740357/
https://www.ncbi.nlm.nih.gov/pubmed/34991698
http://dx.doi.org/10.1186/s13643-021-01872-6
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author Lampit, Amit
Launder, Nathalie H.
Minkov, Ruth
Rollini, Alice
Davey, Christopher G.
Finke, Carsten
Lautenschlager, Nicola T.
Gavelin, Hanna Malmberg
author_facet Lampit, Amit
Launder, Nathalie H.
Minkov, Ruth
Rollini, Alice
Davey, Christopher G.
Finke, Carsten
Lautenschlager, Nicola T.
Gavelin, Hanna Malmberg
author_sort Lampit, Amit
collection PubMed
description BACKGROUND: People with depression often present with concurrent cognitive impairment. Computerized cognitive training (CCT) is a safe and efficacious strategy to maintain or enhance cognitive performance in a range of clinical populations. However, its efficacy in people with depression and how it varies across populations and design factors are currently unclear. METHODS: We searched MEDLINE, EMBASE, and PsycINFO from inception to 13 July 2021 for randomised controlled trials examining the efficacy of CCT vs any control condition on cognitive, mood, psychiatric symptoms, psychosocial, and daily functioning in adults with depression. Eligible samples include studies specifically targeting people with major depressive disorder as well as those with other diagnoses where at least 50% of the sample meets the clinical criteria for depression, with the exception of major psychiatric disorders or dementia. The primary outcome is change in the overall cognitive performance. Multivariate analyses will be used to examine the effect sizes on each outcome category as well as possible effect modifiers and correlations between categories. The risk of bias will be assessed using the Cochrane risk of bias tool version 2. DISCUSSION: To the best of our knowledge, this will be the first systematic review and meta-analysis of narrowly defined CCT across clinical populations with depression. We aim to investigate not only whether CCT is efficacious for cognition, but also how such effects vary across design factors, what other clinically relevant outcomes might respond to CCT, and the extent to which they differ across populations. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42020204209 SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13643-021-01872-6.
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spelling pubmed-87403572022-01-07 Computerized cognitive training in people with depression: a protocol for a systematic review and meta-analysis Lampit, Amit Launder, Nathalie H. Minkov, Ruth Rollini, Alice Davey, Christopher G. Finke, Carsten Lautenschlager, Nicola T. Gavelin, Hanna Malmberg Syst Rev Protocol BACKGROUND: People with depression often present with concurrent cognitive impairment. Computerized cognitive training (CCT) is a safe and efficacious strategy to maintain or enhance cognitive performance in a range of clinical populations. However, its efficacy in people with depression and how it varies across populations and design factors are currently unclear. METHODS: We searched MEDLINE, EMBASE, and PsycINFO from inception to 13 July 2021 for randomised controlled trials examining the efficacy of CCT vs any control condition on cognitive, mood, psychiatric symptoms, psychosocial, and daily functioning in adults with depression. Eligible samples include studies specifically targeting people with major depressive disorder as well as those with other diagnoses where at least 50% of the sample meets the clinical criteria for depression, with the exception of major psychiatric disorders or dementia. The primary outcome is change in the overall cognitive performance. Multivariate analyses will be used to examine the effect sizes on each outcome category as well as possible effect modifiers and correlations between categories. The risk of bias will be assessed using the Cochrane risk of bias tool version 2. DISCUSSION: To the best of our knowledge, this will be the first systematic review and meta-analysis of narrowly defined CCT across clinical populations with depression. We aim to investigate not only whether CCT is efficacious for cognition, but also how such effects vary across design factors, what other clinically relevant outcomes might respond to CCT, and the extent to which they differ across populations. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42020204209 SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13643-021-01872-6. BioMed Central 2022-01-06 /pmc/articles/PMC8740357/ /pubmed/34991698 http://dx.doi.org/10.1186/s13643-021-01872-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Protocol
Lampit, Amit
Launder, Nathalie H.
Minkov, Ruth
Rollini, Alice
Davey, Christopher G.
Finke, Carsten
Lautenschlager, Nicola T.
Gavelin, Hanna Malmberg
Computerized cognitive training in people with depression: a protocol for a systematic review and meta-analysis
title Computerized cognitive training in people with depression: a protocol for a systematic review and meta-analysis
title_full Computerized cognitive training in people with depression: a protocol for a systematic review and meta-analysis
title_fullStr Computerized cognitive training in people with depression: a protocol for a systematic review and meta-analysis
title_full_unstemmed Computerized cognitive training in people with depression: a protocol for a systematic review and meta-analysis
title_short Computerized cognitive training in people with depression: a protocol for a systematic review and meta-analysis
title_sort computerized cognitive training in people with depression: a protocol for a systematic review and meta-analysis
topic Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740357/
https://www.ncbi.nlm.nih.gov/pubmed/34991698
http://dx.doi.org/10.1186/s13643-021-01872-6
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