Impaired tricarboxylic acid cycle flux and mitochondrial aerobic respiration during isoproterenol induced myocardial ischemia is rescued by bilobalide

There is an urgent need to elucidate the pathogenesis of myocardial ischemia (MI) and potential drug treatments. Here, the anti-MI mechanism and material basis of Ginkgo biloba L. extract (GBE) were studied from the perspective of energy metabolism flux regulation. Metabolic flux analysis (MFA) was...

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Detalles Bibliográficos
Autores principales: Wang, Zhe, Zhang, Fan, Liu, Wei, Sheng, Ning, Sun, Hua, Zhang, Jinlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740385/
https://www.ncbi.nlm.nih.gov/pubmed/35028182
http://dx.doi.org/10.1016/j.jpha.2020.08.008