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Association between past oral contraceptive use and the prevalence of hypertension in postmenopausal women: the fifth (2010–2012) Korea National Health and Nutrition Examination Survey (KNHANES V)
BACKGROUND: There is little evidence as to whether the use of oral contraceptives(OC) during the fertile years affects the development of postmenopausal hypertension. This study aimed to evaluate the association between past use of OC and development of hypertension in postmenopausal women. METHODS:...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740434/ https://www.ncbi.nlm.nih.gov/pubmed/34991554 http://dx.doi.org/10.1186/s12889-021-12410-3 |
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author | Lee, JungJu Jeong, Hyunsuk Yoon, Joo Hee Yim, Hyeon Woo |
author_facet | Lee, JungJu Jeong, Hyunsuk Yoon, Joo Hee Yim, Hyeon Woo |
author_sort | Lee, JungJu |
collection | PubMed |
description | BACKGROUND: There is little evidence as to whether the use of oral contraceptives(OC) during the fertile years affects the development of postmenopausal hypertension. This study aimed to evaluate the association between past use of OC and development of hypertension in postmenopausal women. METHODS: This was a cross-sectional study conducted using data from the Fifth Korea National Health and Nutrition Examination Survey of postmenopausal women. Subjects were classified into three groups based on past OC use duration: nonusers, short-term users(0–30 months), and long-term users(≥ 30 months). We evaluated the development of hypertension in women after menopause. A multivariable logistic regression model was used to identify the association between the use of OC during the fertile years and the prevalence of hypertension after menopause following adjustment for potential confounding factors. RESULTS: Of the 3,386 postmenopausal women, 2,713 were nonusers of OC, 489 were short-term users, and 184 were long-term users. Women who had used OC for 30 months or more had a significantly greater prevalence of hypertension after menopause than those who had never taken OC. The association between taking OC for 30 months or more during the fertile years and the prevalence of hypertension after menopause was significant following adjustment for potential confounding factors (adjusted OR:1.75; 95%CI:1.12–2.74). CONCLUSION: This study identified an association between past OC use and an increased prevalence of hypertension in postmenopausal women. Our results suggest that long-term use of OC during the fertile years can be an important risk factor for subsequent hypertension after menopause. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-021-12410-3. |
format | Online Article Text |
id | pubmed-8740434 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-87404342022-01-07 Association between past oral contraceptive use and the prevalence of hypertension in postmenopausal women: the fifth (2010–2012) Korea National Health and Nutrition Examination Survey (KNHANES V) Lee, JungJu Jeong, Hyunsuk Yoon, Joo Hee Yim, Hyeon Woo BMC Public Health Research BACKGROUND: There is little evidence as to whether the use of oral contraceptives(OC) during the fertile years affects the development of postmenopausal hypertension. This study aimed to evaluate the association between past use of OC and development of hypertension in postmenopausal women. METHODS: This was a cross-sectional study conducted using data from the Fifth Korea National Health and Nutrition Examination Survey of postmenopausal women. Subjects were classified into three groups based on past OC use duration: nonusers, short-term users(0–30 months), and long-term users(≥ 30 months). We evaluated the development of hypertension in women after menopause. A multivariable logistic regression model was used to identify the association between the use of OC during the fertile years and the prevalence of hypertension after menopause following adjustment for potential confounding factors. RESULTS: Of the 3,386 postmenopausal women, 2,713 were nonusers of OC, 489 were short-term users, and 184 were long-term users. Women who had used OC for 30 months or more had a significantly greater prevalence of hypertension after menopause than those who had never taken OC. The association between taking OC for 30 months or more during the fertile years and the prevalence of hypertension after menopause was significant following adjustment for potential confounding factors (adjusted OR:1.75; 95%CI:1.12–2.74). CONCLUSION: This study identified an association between past OC use and an increased prevalence of hypertension in postmenopausal women. Our results suggest that long-term use of OC during the fertile years can be an important risk factor for subsequent hypertension after menopause. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-021-12410-3. BioMed Central 2022-01-06 /pmc/articles/PMC8740434/ /pubmed/34991554 http://dx.doi.org/10.1186/s12889-021-12410-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Lee, JungJu Jeong, Hyunsuk Yoon, Joo Hee Yim, Hyeon Woo Association between past oral contraceptive use and the prevalence of hypertension in postmenopausal women: the fifth (2010–2012) Korea National Health and Nutrition Examination Survey (KNHANES V) |
title | Association between past oral contraceptive use and the prevalence of hypertension in postmenopausal women: the fifth (2010–2012) Korea National Health and Nutrition Examination Survey (KNHANES V) |
title_full | Association between past oral contraceptive use and the prevalence of hypertension in postmenopausal women: the fifth (2010–2012) Korea National Health and Nutrition Examination Survey (KNHANES V) |
title_fullStr | Association between past oral contraceptive use and the prevalence of hypertension in postmenopausal women: the fifth (2010–2012) Korea National Health and Nutrition Examination Survey (KNHANES V) |
title_full_unstemmed | Association between past oral contraceptive use and the prevalence of hypertension in postmenopausal women: the fifth (2010–2012) Korea National Health and Nutrition Examination Survey (KNHANES V) |
title_short | Association between past oral contraceptive use and the prevalence of hypertension in postmenopausal women: the fifth (2010–2012) Korea National Health and Nutrition Examination Survey (KNHANES V) |
title_sort | association between past oral contraceptive use and the prevalence of hypertension in postmenopausal women: the fifth (2010–2012) korea national health and nutrition examination survey (knhanes v) |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740434/ https://www.ncbi.nlm.nih.gov/pubmed/34991554 http://dx.doi.org/10.1186/s12889-021-12410-3 |
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