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Exome sequencing of glioblastoma-derived cancer stem cells reveals rare clinically relevant frameshift deletion in MLLT1 gene

BACKGROUND: Glioblastoma multiforme (GBM) is a heterogeneous CNS neoplasm which causes significant morbidity and mortality. One reason for the poor prognostic outcome of GBM is attributed to the presence of cancer stem cells (CSC) which confer resistance against standard chemo- and radiotherapeutics...

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Detalles Bibliográficos
Autores principales:	Marei, Hany E., Althani, Asmaa, Afifi, Nahla, Hasan, Anwarul, Caceci, Thomas, Felsani, Armando, Tringali, Giuseppe, Cifola, Ingrid, Pozzoli, Giacomo, Cenciarelli, Carlo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740446/ https://www.ncbi.nlm.nih.gov/pubmed/34996478 http://dx.doi.org/10.1186/s12935-021-02419-4

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